“…The “good news” is that vorapaxar per se can be most definitely exonerated from the harm observed for stroke prevention, and especially from alarming ICH numbers. 14 The bad news is that vorapaxar has been approved in May 2014, but it’s clinical utilization is still very low, or even not existing in many remote from US markets. It seems that despite the heavy expense of investing in two mega trials, it is challenging to test vorapaxar as a monotherapy in another head-to-head stroke prevention study against clopidogrel and extended-released dipyridamole.…”