2017
DOI: 10.11603/mcch.2410-681x.2016.v0.i4.7254
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Redox state markers of tumors in patients with colorectal cancer

Abstract: МАРКЕРИ РЕДОКС-СТАНУ ПУХЛИН ХвОРИХ НА РАК ПРЯМОї КИШКИВСТУП. За умов ракової хвороби редокс-стан організму та вогнищ пухлинного росту значною мірою визначається перепрограмуванням мета-болізму мітохондрій та особливостями функ ціо-нування металоферментів, зокрема залізо вміс-них: лактоферину (ЛФ) і трансферину (ТФ). Окис-но-індуковані модифікації генів ЛФ і ТФ при зво-дять до порушення їх залізозв'язувальної та залізотранспортувальної функцій, що спри чиняє накопичення в тканинах і крові "вільного заліза" ("ВЗ… Show more

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Cited by 1 publication
(2 citation statements)
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“…> 45 min group comprised 54 patients (in 46 patients classical PM was used; in 8 patients -modified PM). While the groups differed significantly by the number of the resected ML (n = 4 (1-17) and n = 5 (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19) for < 45 min and ≥ 45 min; р = 0.03), the volumetric analysis of the metastatic tissue proved that the groups were stratified (13.6 ± 5.5 cm 3 and 14.1 ± 8.2 cm 3 ; р = 0.16).…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…> 45 min group comprised 54 patients (in 46 patients classical PM was used; in 8 patients -modified PM). While the groups differed significantly by the number of the resected ML (n = 4 (1-17) and n = 5 (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19) for < 45 min and ≥ 45 min; р = 0.03), the volumetric analysis of the metastatic tissue proved that the groups were stratified (13.6 ± 5.5 cm 3 and 14.1 ± 8.2 cm 3 ; р = 0.16).…”
Section: Methodsmentioning
confidence: 99%
“…Activity of FeS proteins of ETC in mitochondria, lactoferrin (LF) and "free" iron content in the tissue were assessed by electron paramagnetic resonance (EPR) at the temperature of 77 o K in the punched samples stored in liquid nitrogen [9]. The rate of SR and NO generation in mitochondria by NADPH oxidase and indu cible NOS (iNOS) of neutrophils was determined by EPR with spin traps [10,11].…”
Section: Methodsmentioning
confidence: 99%