Reduced alcohol drinking following patterned feeding: Role of palatability and acute contingent availability

Shah, Krishna; Shaw, Cemilia; Sirohi, Smita

doi:10.1016/j.physbeh.2020.113020

Cited by 4 publications

(6 citation statements)

References 39 publications

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“…The shared clinical consequences of chronic and binge HFD intake and chronic EtOH misuse suggest an overlap in the mechanisms by which these factors modulate whole body physiology and central pathologies related to emotional regulation pathways indicated in psychiatric conditions. While we present evidence that HFD and EtOH intake may cross-sensitize binge behaviors and metabolic consequences via overlapping central mechanisms, a better mechanistic understanding of these processes may allow alteration of diets to be of benefit during AUD treatment, as has been suggested in other studies (Brutman et al, 2020;Shah et al, 2020). An important topic not discussed in this review is the effect of HFD and EtOH on microbiome gut-brain interactions.…”

Section: Discussionmentioning

confidence: 54%

Impact of High Fat Diet and Ethanol Consumption on Neurocircuitry Regulating Emotional Processing and Metabolic Function

Coker

Keller

Arnold

et al. 2021

Front. Behav. Neurosci.

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The prevalence of psychiatry disorders such as anxiety and depression has steadily increased in recent years in the United States. This increased risk for anxiety and depression is associated with excess weight gain, which is often due to over-consumption of western diets that are typically high in fat, as well as with binge eating disorders, which often overlap with overweight and obesity outcomes. This finding suggests that diet, particularly diets high in fat, may have important consequences on the neurocircuitry regulating emotional processing as well as metabolic functions. Depression and anxiety disorders are also often comorbid with alcohol and substance use disorders. It is well-characterized that many of the neurocircuits that become dysregulated by overconsumption of high fat foods are also involved in drug and alcohol use disorders, suggesting overlapping central dysfunction may be involved. Emerging preclinical data suggest that high fat diets may be an important contributor to increased susceptibility of binge drug and ethanol intake in animal models, suggesting diet could be an important aspect in the etiology of substance use disorders. Neuroinflammation in pivotal brain regions modulating metabolic function, food intake, and binge-like behaviors, such as the hypothalamus, mesolimbic dopamine circuits, and amygdala, may be a critical link between diet, ethanol, metabolic dysfunction, and neuropsychiatric conditions. This brief review will provide an overview of behavioral and physiological changes elicited by both diets high in fat and ethanol consumption, as well as some of their potential effects on neurocircuitry regulating emotional processing and metabolic function.

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Section: Discussionmentioning

confidence: 54%

Impact of High Fat Diet and Ethanol Consumption on Neurocircuitry Regulating Emotional Processing and Metabolic Function

Coker

Keller

Arnold

et al. 2021

Front. Behav. Neurosci.

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“…Considering that hyper-palatable food is typically consumed during dysregulated eating episodes and activate similar brain reward circuitry as of drugs of abuse, including alcohol, several studies have examined the impact of overconsumption of palatable diets on alcohol (Pekkanen et al, 1978;Yung et al, 1983;Mitchell et al, 1985;Krahn and Gosnell, 1991;DiBattista and Joachim, 1999;Avena et al, 2004;Carrillo et al, 2004;Stickel et al, 2016;Takase et al, 2016;Cook et al, 2017;Gelineau et al, 2017;Sirohi et al, 2017b;Villavasso et al, 2019). While still unclear, many studies have observed a reduction in alcohol drinking (Pekkanen et al, 1978;Forsander and Sinclair, 1988;DiBattista and Joachim, 1999;Takase et al, 2016;Cook et al, 2017;Gelineau et al, 2017;Sirohi et al, 2017a,b;Constant et al, 2018;Villavasso et al, 2019;Shah et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

“…Interestingly, some studies have suggested a bidirectional positive link between HPF intake and alcohol drinking (Pekkanen et al, 1978;Mitchell et al, 1985;Krahn and Gosnell, 1991;Avena et al, 2004;Carrillo et al, 2004). However, studies have also demonstrated reduced alcohol drinking following both sugar-and fat-rich palatable diets exposure (Yung et al, 1983;DiBattista and Joachim, 1999;Stickel et al, 2016;Takase et al, 2016;Cook et al, 2017;Gelineau et al, 2017;Sirohi et al, 2017b;Villavasso et al, 2019;Shah et al, 2020). It is important to note that several procedural/experimental differences among these studies could explain the differential impact of palatable diets on alcohol drinking and have been reviewed recently (Brutman et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Patterned Feeding of a Hyper-Palatable Food (Oreo Cookies) Reduces Alcohol Drinking in Rats

Leon

Shah

Bailey

et al. 2021

Front. Behav. Neurosci.

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While a bidirectional positive link between palatable food intake and alcohol drinking has been suggested, several rodents studies report reduced alcohol drinking following palatable diets exposure. These studies utilized purified rodents’ diets high in sugar/fat; however, the effects of hyper-palatable food (HPF) rich in fat and sugar on alcohol drinking remain unclear. Furthermore, neural substrates involved in HPF-mediated changes in alcohol consumption are poorly understood. Therefore, the present study evaluated the effects of patterned feeding of a hyper-palatable food (Oreo cookies) on alcohol drinking as well as dopamine (DA) and serotonin (5-HT) content in rat’s mesocorticolimbic (medial-prefrontal cortex, orbitofrontal cortex, amygdala, and nucleus accumbens) circuitry. Male Long Evans rats received 8-weeks of intermittent (Mon, Tue, Wed) Oreo cookies access, which induced a patterned feeding, in which rats in the Oreo group overconsumed calories on HPF days whereas underconsumption was observed on chow only (Thu, Fri) days. Following HPF exposure, alcohol consumption was evaluated while patterned feeding continued. Alcohol intake in the Oreo group was significantly lower as compared to the chow controls. However, alcohol intake in the Oreo group increased to the levels seen in the group receiving chow following the suspension of patterned HPF feeding. Finally, DA levels in the nucleus accumbens were significantly greater, whereas its metabolite (DOPAC) levels were lower in the Oreo group compared to the chow controls. Surprisingly, 5-HT levels remained unaltered in all tested brain areas. Together, these data suggest that HPF-associated increased DA availability and reduced DA turnover within mesocorticolimbic circuitry may regulate alcohol drinking following patterned HPF feeding.

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“…Furthermore, Alcoholics Anonymous also suggest sweet-tasting foods consumption to curb alcohol cravings [16]. Several preclinical studies from our laboratory and others have also evaluated the impact of PD consumption on alcohol drinking [17][18][19]. For example, our lab has previously demonstrated a reduced alcohol deprivation effect following intermittent high-fat diet (Int-HFD) access [17] and attenuated alcohol drinking following two weeks of Int-HFD preexposure [18] in Long Evans rats.…”

Section: Introductionmentioning

confidence: 99%

“…Several preclinical studies from our laboratory and others have also evaluated the impact of PD consumption on alcohol drinking [17][18][19]. For example, our lab has previously demonstrated a reduced alcohol deprivation effect following intermittent high-fat diet (Int-HFD) access [17] and attenuated alcohol drinking following two weeks of Int-HFD preexposure [18] in Long Evans rats. The objective of the present study was to compare the impact of two weeks of Int-HFD pre-exposure on subsequent alcohol drinking in lower-drinking Wistar rats, moderately drinking Long Evans rats, and higher-drinking P rats.…”

Section: Introductionmentioning

confidence: 99%

Rat Strain-Specific Differences in Alcohol Intake Following Patterned Feeding of a Palatable Diet

White,

Pham,

Houeye

et al. 2023

The 3rd International Electronic Conference on Nutrients

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Reduced alcohol drinking following patterned feeding: Role of palatability and acute contingent availability

Cited by 4 publications

References 39 publications

Impact of High Fat Diet and Ethanol Consumption on Neurocircuitry Regulating Emotional Processing and Metabolic Function

Impact of High Fat Diet and Ethanol Consumption on Neurocircuitry Regulating Emotional Processing and Metabolic Function

Patterned Feeding of a Hyper-Palatable Food (Oreo Cookies) Reduces Alcohol Drinking in Rats

Rat Strain-Specific Differences in Alcohol Intake Following Patterned Feeding of a Palatable Diet

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