2023
DOI: 10.1186/s12977-023-00626-7
|View full text |Cite
|
Sign up to set email alerts
|

Reduced CCR5 expression among Uganda HIV controllers

Abstract: Background Several mechanisms including reduced CCR5 expression, protective HLA, viral restriction factors, broadly neutralizing antibodies, and more efficient T-cell responses, have been reported to account for HIV control among HIV controllers. However, no one mechanism universally accounts for HIV control among all controllers. In this study we determined whether reduced CCR5 expression accounts for HIV control among Ugandan HIV controllers. We determined CCR5 expression among Ugandan HIV co… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 52 publications
0
1
0
Order By: Relevance
“…CCR5 expression associates with the susceptibility of cells to HIV-1 infection [ 12 , 13 ]. CCR5 density on the surface of CD4 + T-cells is lower in HIV-1-exposed uninfected individuals compared with HIV-1-unexposed individuals [ 14 , 15 ], and in HIV-1 controllers compared with noncontrollers [ 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%
“…CCR5 expression associates with the susceptibility of cells to HIV-1 infection [ 12 , 13 ]. CCR5 density on the surface of CD4 + T-cells is lower in HIV-1-exposed uninfected individuals compared with HIV-1-unexposed individuals [ 14 , 15 ], and in HIV-1 controllers compared with noncontrollers [ 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%