Reduced Disability and Mortality Among Aging Runners

Chakravarty, Eliza F.; Hubert, Helen B.; Lingala, Vijaya B.; Fries, James F.

doi:10.1001/archinte.168.15.1638

Cited by 267 publications

(218 citation statements)

References 42 publications

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“…Health benefits of physical activity for older adults are well documented in terms of reduced mortality (Chakravarty et al 2008), better functional, physical, and psychosocial health (Taylor et al 2004;Hughes et al 2004), more positive affect (Netz et al 2007), reduced risk of falling (Carter et al 2001), better health-related quality of life (Rejeski and Mihalko 2001;Motl and McAuley 2009), and less cognitive decline (Klusmann et al 2010). However, despite this evidence, many older adults are not sufficiently active to enjoy these health benefits (Newsom et al 2004).…”

Section: Physical Activity and Health In Old Agementioning

confidence: 99%

Physical activity intervention in older adults: does a participating partner make a difference?

et al. 2011

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Social integration and social support are expected to facilitate the adoption and maintenance of physical activity. In the context of a physical activity intervention, we distinguished three partner status groups, serving as an indicator of social integration. It was hypothesized that individuals whose partner also participated in the intervention, as opposed to individuals whose partners did not participate, or individuals without an intimate partner, would benefit more in terms of their physical activity. In a second step, a differential prediction pattern of social support on physical activity for each of the three partner status groups was investigated. The study involved 302 men and women (aged 60-95 years) and included two measurement points in time: A baseline assessment with a leaflet intervention to foster physical activity, and a 4-week

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Section: Physical Activity and Health In Old Agementioning

confidence: 99%

Physical activity intervention in older adults: does a participating partner make a difference?

et al. 2011

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“…It starts during the intrauterine environment that influences health outcome at adult age, as low birth weight is associated with an increased risk of diseases [2]. Epidemiological studies have clearly established that a lifelong healthy lifestyle, composed of moderate but regular physical exercise (EX) and a balanced diet, prolongs lifespan and reduces the odds of developing cardiovascular diseases (CVD) [10,16,45,46,59,76]. The detrimental effects of the so-called Western diet (WD) and lifestyle on the cardiovascular system have, therefore, been established by numerous studies showing the contribution of physical inactivity (PI) and poor-quality/high-calorie intake on the development of obesity, hypertension, diabetes, and CVD [9,37].…”

Section: Introductionmentioning

confidence: 99%

Postnatal exposure to voluntary exercise but not the antioxidant catechin protects the vasculature after a switch to an atherogenic environment in middle-age mice

Leblond

Nguyen

Bolduc

et al. 2013

Pflugers Arch - Eur J Physiol

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We aimed to evaluate the lasting functional imprinting of exercise (EX) and catechin (CAT) on the vascular function of middle-age mice switched to a proatherogenic environment. C57BL/6J mice (n=10-15 in each group) fed a regular diet (RD) were exposed from the age of 1 to 9 months either to EX (voluntary running; 2.7± 0.2 km/day), to the polyphenol CAT (30 mg/kg/day in drinking water), or to physical inactivity (PI). At 9 months of age, EX and CAT were stopped and mice either remained on the RD or were fed a Western diet (WD) for an additional 3 months. At 12 months of age, mice from all groups fed a WD had similar body mass, systolic blood pressure, and plasma total cholesterol, glucose, insulin, and isoprostane. Compared to the RD, the WD induced an indomethacin-sensitive aortic endothelium-dependent and independent dysfunction in PI mice (p<0.05) that was prevented by both EX and CAT; this benefit was associated with a higher (p< 0.05) non-nitric oxide/non-prostacyclin endothelium-dependent relaxation. While EX, but not PI or CAT, prevented vascular dysfunction induced by the WD in cerebral arteries, it had no effect in femoral arteries. The profiles of activity of antioxidant enzymes and of proinflammatory gene expression in the aorta suggest a better adaptation of EX>CAT>PI mice to stress. In conclusion, our data suggest that a postnatal exposure to EX, but not to CAT, imprints an adaptive defense capacity in the vasculature against a deleterious change in lifestyle.Correspondence to: Eric Thorin.eric.thorin@umontreal.ca. Electronic supplementary material The online version of this article

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“…A number of prospective studies [26][27][28][29][30][31] and reviews [32,33] demonstrate that physical activity could substantially decrease mortality. However, whether the health benefits of physical activity interact with well-known mortality risk factors, such as obesity, has not been studied extensively.…”

Section: Introductionmentioning

confidence: 99%

Effects of physical activity, body mass index, waist-to-hip ratio and waist circumference on total mortality risk in the Swedish National March Cohort

Bellocco

Jia

et al. 2010

Eur J Epidemiol

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Reduced Disability and Mortality Among Aging Runners

Cited by 267 publications

References 42 publications

Physical activity intervention in older adults: does a participating partner make a difference?

Physical activity intervention in older adults: does a participating partner make a difference?

Postnatal exposure to voluntary exercise but not the antioxidant catechin protects the vasculature after a switch to an atherogenic environment in middle-age mice

Effects of physical activity, body mass index, waist-to-hip ratio and waist circumference on total mortality risk in the Swedish National March Cohort

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