2023
DOI: 10.1101/2023.12.01.569643
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Reduced fetal cerebral blood flow following prenatal drug exposure predicts perinatal mortality

Siara Kate Rouzer,
Anirudh Sreeram,
Rajesh Miranda

Abstract: BackgroundChildren exposed prenatally to alcohol or cannabinoids individually can exhibit growth deficits and increased risk for adverse birth outcomes. However, these drugs are often co-consumed and their combined effects on early brain development are virtually unknown. The blood vessels of the fetal brain emerge and mature during the neurogenic period to support nutritional needs of the rapidly growing brain. Teratogenic exposure during this gestational window may therefore impair fetal cerebrovascular deve… Show more

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