Reduced glutathione and acetylcholinesterase expressions in Perna indica exposed to trivalent arsenic

Rajkumar, Johanna

doi:10.14419/ijbr.v1i1.703

Cited by 8 publications

(9 citation statements)

References 21 publications

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“…Although in recent years the number of studies that investigated the interactions between ChE and NMs have been increasing, generally demonstrating an inhibition of their activity in invertebrates as a consequence of CNTs exposure (De Marchi et al 2017a;Monserrat et al 2017;De Marchi et al 2018a;, opposite results were observed in the present study, showing no inhibition of AChE activity in exposed organisms under both materials and both salinities. Such result may be related to the fact that organisms try to reduce neurotransmitter excess in the synaptic clefts, which was already showed in the bivalve Perna indica exposed to arsenic (As) (Rajkumar, 2013). II) Alteration induced by salinity shifts modifying the sensitivity of the polychaetes and the toxicity of the CNTs was also observed in the present study.…”

Section: Accepted Manuscriptsupporting

confidence: 79%

The influence of Climate Change on the fate and behavior of different carbon nanotubes materials and implication to estuarine invertebrates

Marchi

Neto

Pretti

et al. 2019

Comparative Biochemistry and Physiology Part C: Toxicology &

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Please cite this article as: L. De Marchi, V. Neto, C. Pretti, et al., The influence of climate change on the fate and behavior of different carbon nanotubes materials and implication to estuarine invertebrates, Comparative Biochemistry and Physiology, Part C, https://doi. AbstarctThe widespread use of Carbon nanotubes (CNTs) has been increasing exponentially, leading to a significant potential release into the environment. Nevertheless, the toxic effects of CNTs in natural aquatic systems are related to their ability to interact with abiotic compounds. Considering that salinity variations are one of the main challenges in the environment and thus may influence the behavior and toxicity of CNTs, a laboratory experiment was performed exposing the tube-building polychaete Diopatra neapolitana (Delle Chiaje 1841) for 28 days to pristine multi-walled carbon nanotube MWCNTs and carboxylated MWCNTs, maintained at control salinity 28 and low salinity 21. An innovative approach based on thermogravimetric analysis was adopted for the first time to assess the presence of MWCNTs aggregates in the organisms Both CNTs generated toxic impacts in terms of regenerative capacity, energy reserves and metabolic capacity as well as oxidative and neuro status, however greater toxic impacts were observed in polychaetes exposed to carboxylated MWCNTs. Moreover, both CNTs maintained under control salinity (28) generated higher toxic impacts in the polychaetes compared to individuals maintained under low salinity (21), indicating that exposed polychaetes tend to be more sensitive to the alteration induced by salinity variations on the chemical behavior of both MWCNTs in comparison to salt stress.

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Section: Accepted Manuscriptsupporting

confidence: 79%

The influence of Climate Change on the fate and behavior of different carbon nanotubes materials and implication to estuarine invertebrates

Marchi

Neto

Pretti

et al. 2019

Comparative Biochemistry and Physiology Part C: Toxicology &

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“…In what regards to the neurotoxic impacts, both conditions A and a inhibited AChE activity, with higher injuries when organisms were exposed to the highest As concentration (contaminated seawater). Rajkumar (2013) also showed that As concentrations (80 µg/L) induced neurotoxicity in mussels. A similar pattern was shown by other authors with clams (e.g.…”

Section: Accepted Manuscriptmentioning

confidence: 87%

Remediation of arsenic from contaminated seawater using manganese spinel ferrite nanoparticles: Ecotoxicological evaluation in Mytilus galloprovincialis

Coppola

Tavares

Henriques

et al. 2019

Environmental Research

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In the last decade different approaches have been applied for water remediation purposes, including the use of nanoparticles(NPs) to remove metals and metalloids from water. Although studies have been done on the toxic impacts of such NPs, very scarce information is available on the impacts of water after decontamination when discharged into aquatic environments. In this way, the present study we aimed to evaluate the ecotoxicological safety of seawater previously contaminated with arsenic (As) and remediated by using manganese-ferrite (MnFe2O4) nanoparticles (NPs). For this, mussels Mytilus galloprovincialis were exposed for 28 days to different conditions, including clean seawater (control), As (1000 µg L-1) contaminated and remediated (As 70 µg L-1) seawater, water containing manganese-ferrite (MnFe2O4) nanoparticles (NPs) (50 mg L-1) with and with the presence of As. At the end of exposure, concentrations of As in mussels tissues were quantified and biomarkers related to mussels' metabolism and oxidative stress status were evaluated. Results revealed that mussels exposed to water contaminated with As and to As+NPs accumulated significantly more As (between 62% to 76% more) than those exposed to remediated seawater. Regarding biomarkers, our findings demonstrated that in comparison to remediated seawater (conditions a, b, c) mussels exposed to contaminated seawater (conditions A, B, C) presented significantly lower metabolic activity, lower expenditure of energy reserves, activation of antioxidant and biotransformation defences, higher lipids and protein damages and greater AChE inhibition. Furthermore, organisms exposed to As, NPs or As+NPs revealed similar biochemical effects, both before and after water decontamination. In conclusion, the present study suggests that seawater previously contaminated with As and remediated by manganese-ferrite (MnFe2O4) NPs presented significantly lower toxicity than As contaminated water, evidencing the potential use of these NPs to remediate seawater contaminated with As and its safety towards marine systems after discharges to these environments.

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“…Table 1 shows any significant differences of the average difference of physicochemical properties and nutrient salts dissolved of seawater before and after the tests. Besides, the effects of the variation of the abiotic parameters have been reported on CAT activity and bioaccumulation of heavy metals [12,[22][23][24][25][26]. Moreover, temperature and salinity affected the filtration rate of mussels and the amount of oxygen consumed.…”

Section: Some Physicochemical Properties and Nutrient Saltsmentioning

confidence: 99%

“…indicates that the total level of protein had variation with no linearity in the Cd, Pb, and Cu treated P. perna. Protein reserves appear to be affected by the chemical pollutant [25,26]. However, Rajkumar (2013) [26] reported that the metabolites of mussels given by the level of total protein can be affected by heavy metal exposures.…”

Section: Tissue Metal Contentmentioning

confidence: 99%

Catalase Activity in Brown Mussels (Perna perna) under Acute Cadmium, Lead, and Copper Exposure and Depuration Tests

Boudjema

Kourdali²,

Bounakous³

et al. 2014

Journal of Marine Biology

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Brown mussels (Perna perna) were exposed to cadmium (Cd), lead (Pb), and copper (Cu) concentrations under acute exposure and exposure-depuration tests for the estimation of biochemical biomarker catalase (CAT). The acute tests showed accumulated Cd, Pb, and Cu inPerna pernacorrelated linearly with the exposure concentrations (R2=0.794,R2=0.891, andR2=0.985for Cd, Pb, and Cu, resp.). The results of CAT increased significantly in tissues of treatment mussels after 72 h exposure when compared to control. The values of total protein were disturbed in exposed groups when compared with control. These results suggest that metabolites and catalase activity were affected by heavy metal exposures. Analysis using the Spearman rank correlation coefficient showed that the CAT activity appeared to have a significant positive correlativity (Rs=0.921,Rs=0.949, andRs=0.949for Cd, Pb, and Cu, resp.) with the accumulated Cd, Pb, and Cu concentrations, respectively. The result of exposure-depuration tests showed that there is a general tendency for CAT to decrease in depuration phase, suggesting that the induction of catalase is metal and/or mixture of metals dependent.

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Reduced glutathione and acetylcholinesterase expressions in Perna indica exposed to trivalent arsenic

Cited by 8 publications

References 21 publications

The influence of Climate Change on the fate and behavior of different carbon nanotubes materials and implication to estuarine invertebrates

The influence of Climate Change on the fate and behavior of different carbon nanotubes materials and implication to estuarine invertebrates

Remediation of arsenic from contaminated seawater using manganese spinel ferrite nanoparticles: Ecotoxicological evaluation in Mytilus galloprovincialis

Catalase Activity in Brown Mussels (Perna perna) under Acute Cadmium, Lead, and Copper Exposure and Depuration Tests

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