Reduced Growth Hormone Response to Anaerobic Exercise Among Children With Overweight and Obesity

Hejla, Duha; Dror, Nitzan; Pantanowitz, Michal; Nemet, Damir; Eliakim, Alon

doi:10.1519/jsc.0000000000003798

Cited by 4 publications

(3 citation statements)

References 25 publications

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“…As exercise impacts many of the endocrine system's homeostatic functions, these interactions are especially important for the GH/IGF-I axis 39,40 . Exercise promotes anabolic components of the growth GH-IGF-axis in children 41 ; on the contrary, the typical increase in circulating GH seen in response to exercise would be attenuated in children with disease, such as ADHD 42 , overweight, and obesity 43 . As expected, our results revealed that different types of exercise can effectively improve GH and IGF-I level in children, such as physical activity, intellectual activity, physical combine with intellectual activity.…”

Section: Discussionmentioning

confidence: 99%

Research on the effect of different aerobic activity on physical fitness and executive function in primary school students

Ren,

Chu,

Zhang

et al. 2024

Sci Rep

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To evaluate the effect of 16 weeks of different aerobic activity on physical fitness and executive functions in primary school students. 90 right-handed students from China (Boys = 46; Girls = 44) participated in our study and were randomly separated into four groups: 20 in the control group (Con), 23 in the physical activity group (PA), 25 in the intellectual activity group (IA), 22 in the physical activity and intellectual activity group (PA + IA). The students in PA, IA and PA + IA group received aerobic exercise program lasted 40 min daily, 4 days a week for 16 weeks, regular physical activity in the PA group, intellectual activity in the IA group, physical activity couple with intellectual activity in the PA + IA group, respectively. All the students participate the experiment for body composition, physical fitness (cardiopulmonary fitness, muscle strength, speed sensitivity, flexibility quality), executive functions and saliva analysis test before and after 16 weeks. There was no significant effect of 16 weeks different aerobic exercise interventions on body composition before and after exercise interventions among four groups in children (p > 0.05). The results were obtained by inter-group and intra-group comparisons that different exercise interventions (physical activity, intellectual activity, physical combine with intellectual activity), all can significantly improve physical fitness parameters (cardiopulmonary fitness, muscle strength, speed sensitivity and flexibility quality), and executive functions parameters (inhibitory control, working memory, reaction time cognitive flexibility), as well as the concentration of saliva GH and IGF-I (p < 0.05) in children. Our experiment further demonstrated that the improvement effect of the two exercises together is more significant than that of the single exercise ways. Both physical and intellectual activity can effectively improve physical fitness and executive function in children, and the improvement effect of the two exercises together is more significant than that of the single exercise ways.

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Section: Discussionmentioning

confidence: 99%

Research on the effect of different aerobic activity on physical fitness and executive function in primary school students

Ren,

Chu,

Zhang

et al. 2024

Sci Rep

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“…Physiologically, obesity has become a risk factor that may affect the release or regulation of growth hormones (Høgild et al, 2019). Hejla, Dror, Pantanowitz, Nemet, & Eliakim (2022) reported that GH secretion was lower in overweight and obese individuals than in normal weight individuals. The association of obese individuals with low growth hormone levels was also reported by Savastano, Di Somma, Barrea, & Colao (2014) Obesity causes a decrease in GH secretion, resulting in increased fat mass, decreased lipolysis, and decreased insulin sensitivity, leading to metabolic disorders (Høgild et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

“…However, research by Sasaki et al (2014) found no change in GH response after 4 weeks (3 days/week, 12 sessions total) of high-intensity interval training (10 sets of 1 min pedaling at 85% VO 2 max with a 30 s rest between sets) in sedentary men. In another case, research conducted by Hejla, Dror, Pantanowitz, Nemet, & Eliakim (2022) a single session of the Wingate anaerobic test (WAnT) with 10 bouts of 15-second cycling separated by 1 minute of rest significantly reduced GH levels in children with overweight and obesity compared with those with normal weight. Meanwhile, a study by Deemer et al (2018) used a crossover design in five young women to compare the effects of high-intensity interval exercise (HIE) (four 30-s "all-out" sprints with 4.5 min of active recovery) and 30min continuous cycling with moderate-intensity continuous exercise (MOD) on GH secretion.…”

Section: Introductionmentioning

confidence: 99%

Aerobic Exercise Increases Release of Growth Hormone in the Blood Circulation in Obese Women

Pranoto,

Rejeki,

Miftahussurur

et al. 2023

Retos

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Physical exercise is one of the modulators in increasing the release of growth hormone (GH) levels in blood circulation, but the effective exercise model for obese subjects is still being debated. Therefore, this study aims to prove the effect of aerobic exercise on increasing the release of GH levels in the blood circulation in obese women. A total of 20 obese adult women, aged 21.00 ± 1.08 years were selected to be subjects in the study and were given one aerobic exercise intervention by running on a treadmill at moderate-intensity (60-70% HRmax) for 40 minutes. The ELISA method was used to measure the release of GH levels in all samples (pre- and post-exercise). Statistical analysis in this study used an independent sample t-test with a significant level of 5%. The results showed that the release of GH levels in the blood circulation was found to be higher in post-exercise compared to pre-exercise after one session of aerobic exercise (484.92±128.29 vs 892.63±273.54 pg/mL; p=0.001) and has a large effect size with a Cohen's d value of 1.909. GH levels in the post-exercise blood circulation in the aerobic exercise group (Exr) were also found to be higher than the GH levels in the control group (Ctr) (892.63±273.54 vs 542.97±140.01 pg/mL; p=0.003) and has a large effect size with a Cohen's d value of 1.609. This study proves that one session of aerobic exercise with moderate intensity increases the release of circulating GH levels in obese women. Therefore, aerobic exercise with moderate intensity can be used as an alternative therapy option to increase the release of circulating GH levels in individuals with obesity. Keywords: aerobic exercise, growth hormone, metabolism, obesity.

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Physiological response of endurance exercise as a growth hormone mediator in adolescent women’s

Sugiharto

Merawati

Pranoto

et al. 2022

Journal of Basic and Clinical Physiology and Pharmacology

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Objectives Overweight status decreases the growth hormone (GH) secretion, thus, increasing the risk factors for medical complications. However, proper exercise is reported to enhance GH and affect the energy balance. Therefore, exercise is proclaimed to be an accurate and engaging therapy to increase GH in preventing overweight. This study aims to investigate the physiological response of exercise in mediating the increase of GH secretion in female adolescents. Methods 22 overweight women aged 19–20 years old, with maximal oxygen consumption of 27–35 mL/kg/min, were selected as sample size. They were divided into three groups, namely (CONT, n=7) Control, (MIEE, n=7) Moderate-intensity interval endurance exercise, and (MCEE, n=8) Moderate-intensity continuous endurance exercise. The exercise was carried out by running for 30–35 min using treadmills with an intensity of 60–70% HRmax. The blood sampling for GH examination was carried out four times before exercise, 10 min, 6 h, and 24 h after exercise. The enzyme-linked immunosorbent assay (ELISA) was used to measure the GH and IGF-1 levels. The data analysis was carried out using a one-way ANOVA test, with a significance level of 5%. Results The results of the one-Way ANOVA test suggested a significantly different average GH and IGF-1 before and after the exercise between the three groups (CON, MIEE, and MCEE) (p≤0.05). Conclusions MCEE increases the GH and IGF-1 levels more considerably than MIEE. Therefore, exercise is a mediator to increase GH and IGF-1 secretion in overweight individuals. Exercise could be a viable therapy for overweight people.

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Reduced Growth Hormone Response to Anaerobic Exercise Among Children With Overweight and Obesity

Cited by 4 publications

References 25 publications

Research on the effect of different aerobic activity on physical fitness and executive function in primary school students

Research on the effect of different aerobic activity on physical fitness and executive function in primary school students

Aerobic Exercise Increases Release of Growth Hormone in the Blood Circulation in Obese Women

Physiological response of endurance exercise as a growth hormone mediator in adolescent women’s

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