2011
DOI: 10.1016/j.fsi.2010.12.020
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Reduced gut bacterial translocation in European sea bass (Dicentrarchus labrax) fed mannan oligosaccharides (MOS)

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Cited by 77 publications
(79 citation statements)
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“…However, fold width was reduced in fish fed cMOS, which could be due to a reduced engrossment of the submucosa within the fold basis. Besides, the presence of thinner folds in fish fed cMOS may result in a higher absorptive surface by increasing the number of folds by intestinal section in agreement with previous studies in the same fish species with the first generation product [11] and in relation to the enhanced SGR found in the present study. Indeed, further morphometric studies are being conducted in order to corroborate this hypothesis.…”
Section: Discussionsupporting
confidence: 93%
“…However, fold width was reduced in fish fed cMOS, which could be due to a reduced engrossment of the submucosa within the fold basis. Besides, the presence of thinner folds in fish fed cMOS may result in a higher absorptive surface by increasing the number of folds by intestinal section in agreement with previous studies in the same fish species with the first generation product [11] and in relation to the enhanced SGR found in the present study. Indeed, further morphometric studies are being conducted in order to corroborate this hypothesis.…”
Section: Discussionsupporting
confidence: 93%
“…The ability of orally-delivered immunostimulants to enhance innate immunity seems to be different in the gut, compared to other mucosal surfaces. This is illustrated by a recent study where mannan was orally administered to seabass and gut but not skin mucus innate immune functions were significantly modulated [122]. On the other hand, feeding ergosan or fermented Saccharomyces cerevisiae to rainbow trout enhances skin mucus innate immune parameters, indicating some connection between both compartments [123, 124].…”
Section: Exploiting Mucosal Immunity For Immunotherapymentioning
confidence: 99%
“…In fish as in mammals, it has been shown that the mucus layer is continuously secreted and thereby washes away trapped particles. The main components of this mucus layer are secreted mucins (20,21). In mammals, each mucin can carry on the order of 100 different carbohydrate structures, which provides a vast array of potential binding sites for microbes (20).…”
mentioning
confidence: 99%