In view of the lack of effective energy station site optimization method in the existing integrated energy system (IES) planning, and the failure to consider the load characteristics in the division process of the energy supply area of energy stations, a pipeline network layout method of integrated energy system is proposed based on energy station site selection and load complementary characteristics. Firstly, based on the analysis of the interaction between the station and network planning of IES, an alternated optimal method framework of energy station site, energy supply area division and pipe network layout are proposed. Secondly, based on the energy supply radius of the energy station, this paper proposes a method to determine the number of new energy stations, and based on the topological characteristics of the cellular networks, a method of determine the initial energy station site is proposed. Thirdly, considering the complementary load characteristics, the evaluation index and division method of energy supply area of integrated energy station are proposed. Fourthly, aiming at the problem of pipe network layout on the road, a pipe network optimization method based on Kruskal algorithm is proposed, and optimize the direction of load access to the pipe network by the linear optimization model. Fifthly, the calculation method of equivalent energy distance of load and the optimization method of energy station site based on equivalent energy distance are proposed. Finally, the rationality and effectiveness of this method are verified by an example. INDEX TERMS Energy system planning and optimization, pipeline network layout, energy station site selection, load energy distance, load complementary characteristics.