Reduced variability in pulse wave velocity in depressed patients with suicidal ideation

Khandoker, Ahsan H.; Luthra, Veena; Abouallaban, Yousef; Saha, Simanto; Ahmed, Khawza I.; Mostafa, Raqibul; Chowdhury, Nayeefa; Jelinek, Herbert F.

doi:10.1109/cic.2015.7411097

Cited by 7 publications

(4 citation statements)

References 19 publications

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“…Similar results were reported by Van Sloten et al in the AGES-Reykjavik Study Artery Research [12]. Khandoker et al analyzed the increased incidence of AS, as assessed solely by the PWV or by PWV and Fingertip Photo-Plethysmography in smaller groups of depressed patients with suicidal intention, but without comorbid CVD [20]. Other results of recent meta-analyses of prospective cohort studies, conducted on subjects that were initially without CVD, indicate that depression was associated with a 30% increased risk of future coronary events [21,22].…”

Section: Discussionsupporting

confidence: 74%

Aspects of diastolic dysfunction in patients with new and recurrent depression

Tudoran

Ciocârlie

et al. 2020

PLoS ONE

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ObjectiveThe main objective of this study was to evidence the potential impact of the intensity, duration and recurrence of depression on the development of arterial stiffness (AS) leading to left ventricular hypertrophy (LVH) and diastolic dysfunction (DD) in patients with new onset depression (NOD) and recurrent depression (RD) in comparison to 33 control subjects without depression. Another aim was to identify potential predictive factors regarding the occurrence of diastolic dysfunction (DD). MethodsOur study group included 58 patients diagnosed with NOD and 128 diagnosed with RD, without any previously diagnosed significant heart diseases. The intensity of depression was evaluated by means of the Montgomery-Asberg Depression Rating Scale (MADRS). Assessment of pulse wave velocity (PWV), left ventricular mass index (LVMI) and echocardiographic parameters characterizing DD were performed for each patient. ResultsThe cardiology evaluations suggested an increased prevalence of AS in all patients, of significantly higher rate than in controls (p<0.001), which was statistically correlated with the severity and duration of depression. Another significant finding was an increased prevalence of DD (29.31% and 63.28%, respectively; p<0.001) correlated with the MADRS score, total duration and number of recurrences/relapses. The multivariate logistic regression analysis identified PWV, the intensity and duration of depression as significant predictive factors for the occurrence of DD. ConclusionsIn our study, diastolic dysfunction was a common finding among patients with RD, but it was also noted, to a lesser extent, in those suffering with NOD. DD was associated with altered AS, and strongly correlated with the intensity and the duration of depressive symptoms. The

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Section: Discussionsupporting

confidence: 74%

Aspects of diastolic dysfunction in patients with new and recurrent depression

Tudoran

Ciocârlie

et al. 2020

PLoS ONE

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“…Poongothai et al determined the incidence of MDD, AS, but also of IMT, in a cohort of 1505 participants included in the Chennai Urban Rural Epidemiology Study (19), which evidenced increased AS and IMT values in depressed patients. Khandoker et al, analysed the increased incidence of AS, as assessed solely by PWV and by PWV and Fingertip Photo-Plethysmography in smaller groups of depressed patients with suicidal intention, but without comorbid CVD (20). Other results of recent metaanalyses of prospective cohort studies, conducted on subjects that were initially free of CVD, indicate that depression was associated with a 30% increased risk of future coronar y events [10,12,13,21].…”

Section: Resultsmentioning

confidence: 99%

Impact of Therapy with Selective Serotonine-Reuptake Inhibitors on the Evolution of Subclinical Atherosclerosis in Patients with Depressive Disorder

Tudoran¹,

Giurgi-Oncu²,

Andor³

et al. 2019

Rev. Chim.

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The aim of this study is to highlight the impact of therapy with Sertraline on the AS alterations, in a group of 128 patients with MDD, but without significant CVD or risk factors for atherosclerosis. A secondary goal was to analyze whether there are statistically significant correlations between AS and the intensity of the current depressive episode, as assessed by using the Montgomery-Asberg Depression Rating Scale (MADRS), while also taking into account the duration of MDD.

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“…Furthermore, it is related to the mental state. It has been indicated that depressed patients who consider suicide exhibit fluctuating PWVs [8].…”

Section: B Pulse Wave Velocity (Pwv)mentioning

confidence: 99%

Multimodal Cardiovascular Information Monitor Using Piezoelectric Transducers for Wearable Healthcare

Okano

Izumi

Katsuura

et al. 2018

J Sign Process Syst

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This article describes a multimodal cardiovascular information measurement method using a wearable device composed of piezoelectric transducers. Cardiovascular diseases are increasing with the aging population, and they constitute a significant portion of the causes of death and long-term care. In recent years, daily-life monitoring using wearable sensor devices has attracted particular attention for the prevention and early detection of cardiovascular diseases. However, recent wearable devices can only measure limited cardiovascular information such as the heart rate. In contrast, the proposed method can simultaneously measure heart rate variability, pulse wave propagation velocity, and blood flow velocity using only a piezoelectric transducer array.

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Reduced variability in pulse wave velocity in depressed patients with suicidal ideation

Cited by 7 publications

References 19 publications

Aspects of diastolic dysfunction in patients with new and recurrent depression

Aspects of diastolic dysfunction in patients with new and recurrent depression

Impact of Therapy with Selective Serotonine-Reuptake Inhibitors on the Evolution of Subclinical Atherosclerosis in Patients with Depressive Disorder

Multimodal Cardiovascular Information Monitor Using Piezoelectric Transducers for Wearable Healthcare

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