This manuscript presents the application of a recently developed noise reduction technology, constituted by poro-serrated stator blades on a full-scale aircraft model, in order to reduce rotor-stator interaction noise in the fan stage. This study was carried out using the commercial lattice Boltzmann solver 3DS-SIMULIA PowerFLOW. The simulation combines the airframe of the NASA High-Lift Common Research Model with an upscaled fan stage of the source diagnostic test rig. The poro-serrations on the stator blades have been modeled based on a metal foam with two different porosity values. The results evidence that the poro-serrations induce flow separation on the stator blades, particularly near the fan-stage hub. Consequently, the thrust generated by the modified fan stage is lower and the broadband noise emission at low frequencies is enhanced. Nevertheless, the tonal noise components at the blade-passage frequency and its harmonics are mitigated by up to 9 dB. The poro-serrations with lower porosity achieve a better trade-off between noise emission and thrust penalty. An optimization attempt was carried out by limiting the application of porosity near the tip of the stator blades. The improved leading-edge treatment achieves a total of 1.5 dB in sound power level reduction while the thrust penalty is below 1.5%. This demonstrates that the aerodynamic effects of a leading-edge treatment should be taken into account during the design phase to fully benefit from its noise reduction capability.