Reducing Intracranial Pressure May Increase Survival among Patients with Bacterial Meningitis

Lindvall, Peter; Ahlm, Clas; Ericsson, Madelene; Gothefors, Leif; Naredi, Silvana; Koskinen, Lars-Owe D.

doi:10.1086/380970

Cited by 122 publications

(79 citation statements)

References 23 publications

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“…Elevated intracranial pressure is often a feature of severe tuberculous meningitis, 23 cryptococcal meningitis 24 and severe bacterial meningitis. 25 Although not as well known as other types of meningitis, raised intracranial pressure is found in rickettsial meningitis as well. In 1986, Wenzel and others 26 reported five cases of acute febrile cerebrovasculitis with increased intracranial pressure presumably caused by rickettsial infection.…”

Section: Discussionmentioning

confidence: 99%

Abducens Nerve Palsy and Meningitis by Rickettsia typhi

Moy

Ooi

2015

The American Society of Tropical Medicine and Hygiene

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Abstract. Patients with rickettsial infection may present with encephalitis or meningitis but neurologic involvement is rare in murine typhus. Here, we report two patients with Rickettsia typhi meningitis who presented with cranial neuropathy, presumably caused by two distinct disease processes. Recognition of the disease manifestations is important because rickettsial infections are potentially associated with significant morbidity. Simple effective treatments are available.

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Section: Discussionmentioning

confidence: 99%

Abducens Nerve Palsy and Meningitis by Rickettsia typhi

Moy

Ooi

2015

The American Society of Tropical Medicine and Hygiene

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“…Fifteen patients with a GCS score of < 9 were included in the other study, and all but one had elevated ICP. Ten patients survived, resulting in a mortality rate of 33% (Lindvall et al, 2004). These results can be compared with a previously reported mortality rate of 62% in a comparable group of meningitis patients (Schutte and van der Meyden, 1998).…”

Section: Clinical Outcome Studiesmentioning

confidence: 54%

Severe traumatic brain injury management and clinical outcome using the Lund concept

2014

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“…Elevated ICP in acute bacterial meningitis is associated with decreased survival. 8 An elevated opening pressure on LP in this setting reflects an acute process, and requires urgent intervention to reduce the risk of brain herniation. In presumed acute bacterial meningitis, if LP reveals an elevated opening pressure, we recommend immediate cessation of CSF removal, treatment with hyperosmolar therapy, consideration of placement of an ICP monitor and CSF diversion, and close monitoring in an ICU.…”

Section: Sectionmentioning

confidence: 99%