Reducing sedentary behaviour and physical inactivity in the workplace: protocol for a review of systematic reviews

Dieterich, Anna Valeria; Müller, André; Akksilp, Katika; Sarin, K C; Dabak, Saudamini Vishwanath; Rouyard, Thomas

doi:10.1136/bmjsem-2020-000909

Cited by 3 publications

(1 citation statement)

References 37 publications

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“…The increased urbanization and technological advancements have been accompanied by a high prevalence of sedentary behaviour (SB) and physical inactivity (PI) worldwide, especially in the workplaces [ 1 , 2 ]. A recent review found that working adults spent about 60% of their waking time in SB and about 4% of the day in moderate to vigorous physical activity (PA) [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of combined training on metabolic profile, lung function, stress and quality of life in sedentary adults: A study protocol for a randomized controlled trial

et al. 2022

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Background Both physical inactivity and sedentary behavior are considered modifiable risk factors for chronic diseases and all-cause mortality. Adult office-workers spend most of their working day in sedentary behaviors, so they are particularly at high risk of developed chronic diseases (e.g., cardiovascular diseases, metabolic disorders like diabetes mellitus, …). It seems important to promote behavioral changes that could prevent or delay metabolic disease development. Evidence supports the use of exercise programs, however, to date there are several knowledge gaps and inconsistencies in the literature regarding the effects of Combined Training (i.e., aerobic plus resistance training) in sedentary healthy adults. This paper outlines an RCT designed to evaluate the effects of a 16-week combined training program on biochemical and immune markers of metabolic disease, lung function, salivary stress hormones and subjective quality of life (primary outcomes), as well as on body composition and physical fitness (secondary outcomes) in sedentary middle-aged office-workers. Furthermore, we aimed to assess the associations between the changes promoted by the exercise program and the different variables studied. Methods and design This is a single-blinded two-arm RCT with parallel groups. A minimum of healthy 40 office-workers aged 40–64 years will be recruited to engage in a 16-week intervention study. After baseline assessments, participants will be randomized to one of the two groups: (1) combined training group or (2) control group. Baseline assessments will be repeated after 8 weeks of intervention (mid-testing) and upon completion of the intervention (post-testing). Discussion This RCT involves a multi-disciplinary approach and seems to be a relevant contribution to understanding the potential role of combined training in improving the metabolic profile, lung function, stress, and quality of life in adults. The results can provide important insights for clinical recommendations and for the optimization of strategies to prevent metabolic disorders in adults with sedentary jobs. Trial registration This trial is registered with ClinicalTrials.gov (registration number: NCT04868240; date of registration April 30, 2021).

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Section: Introductionmentioning

confidence: 99%

Effects of combined training on metabolic profile, lung function, stress and quality of life in sedentary adults: A study protocol for a randomized controlled trial

et al. 2022

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Impact of Breaking up of Sitting Time on Anti-inflammatory Response Induced by Extracellular Vesicles

Padilha,

Antunes,

Jiménez-Maldonado

et al. 2023

CPD

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Physical inactivity and sedentary behaviors (SB) have promoted a dramatic increase in the incidence of a host of chronic disorders over the last century. The breaking up of sitting time (i.e., sitting to standing up transition) has been proposed as a promising solution in several epidemiological and clinical studies. In parallel to the large interest it initially created, there is a growing body of evidence indicating that breaking up prolonged sedentary time (i.e., > 7 h in sitting time) could reduce overall mortality risks by normalizing the inflammatory profile and cardiometabolic functions. Recent advances suggest that the latter health benefits, may be mediated through the immunomodulatory properties of extracellular vesicles. Primarily composed of miRNA, lipids, mRNA and proteins, these vesicles would influence metabolism and immune system functions by promoting M1 to M2 macrophage polarization (i.e., from a pro-inflammatory to anti-inflammatory phenotype) and improving endothelial function. The outcomes of interrupting prolonged sitting time may be attributed to molecular mechanisms induced by circulating angiogenic cells. Functionally, circulating angiogenic cells contribute to repair and remodel the vasculature. This effect is proposed to be mediated through the secretion of paracrine factors. The present review article intends to clarify the beneficial contributions of breaking up sitting time on extracellular vesicles formation and macrophage polarization (M1 and M2 phenotypes). Hence, it will highlight key mechanistic information regarding how breaking up sitting time protocols improves endothelial health by promoting antioxidant and anti-inflammatory responses in human organs and tissues.

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The Flow of Green Exercise, Its Characteristics, Mechanism, and Pattern in Urban Green Space Networks: A Case Study of Nangchang, China

Cai

Gao

Xiao

et al. 2023

Land

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An urban green space network provides safe and green exercise routes for residents. This study selected Nanchang as the study area. Using fitness application data, we explored the mobility of people exercising in the network, i.e., the flow of green exercise. Spatial analysis based on social networks, GIS, and the gravity model was used to analyze the nodes, network characteristics, and mechanism of the flow of green exercise. The results show that there were differences in the hierarchy and attractiveness of nodes. Distance had an important influence on green exercise. It was found that walkers moved between adjacent parks, runners visited more parks and corridors, while cyclists covered longer distances and preferred to explore suburban green spaces. The length of the exercise route in green spaces had a positive effect on mobility. Because of the many combinations of patches and corridors, three flow subnetworks were formed. In addition, the green space network expanded the scope of exercise services in the central node. The management of green spaces should pay attention to the social value of urban green space networks and create a hierarchical and interconnected green space for exercisers.

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Reducing sedentary behaviour and physical inactivity in the workplace: protocol for a review of systematic reviews

Cited by 3 publications

References 37 publications

Effects of combined training on metabolic profile, lung function, stress and quality of life in sedentary adults: A study protocol for a randomized controlled trial

Effects of combined training on metabolic profile, lung function, stress and quality of life in sedentary adults: A study protocol for a randomized controlled trial

Impact of Breaking up of Sitting Time on Anti-inflammatory Response Induced by Extracellular Vesicles

The Flow of Green Exercise, Its Characteristics, Mechanism, and Pattern in Urban Green Space Networks: A Case Study of Nangchang, China

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