Reduction Des Groupes Fonctionnels Nitroaromatiques Par L'Hydrogene en Presence de Palladium Sur Charbon

1H and 13C chemical shifts for acridines: Part XVII. (1,3‐Benzothiazol‐2‐yl)amino‐9(10H)‐acridinone derivatives

“…Thus the amino-imino tautomerism is completely shifted towards BZT1 in this hydrogen-bonded system. In the case of the 2-and 3-substituted compounds 5-8 and 10-12 the substituent effects on the 13 C chemical shifts of acridin-9(10H)-one and 1,3-benzothiazole rings are similar to the literature data. 23,24 Finally, for the 4-substituted compounds 13-15 the broadening of the 1 H and 13 C resonance was indicative of a rate modification of exchange.…”

“…Reductions of nitro to amino derivatives (4, 8, 12 and 16) were performed in DMF at 40 psi with Pd/C catalyst. 13 Each compound was purified by flash column chromatography. 1 H and 13 C NMR spectra were recorded at 300 K using a Bruker Avance DRX 500 spectrometer equipped with a 5 mm gradient inverse detection TXI cryoprobe.…”

“…6 As part of our program on modified acridines as topoisomerase-target drug, 7,8 we were interested in preparing new acridine compounds with a supplementary benzothiazole ring since the latter compound also showed interesting activity as an anti-cancer drug. In this paper we report the complete 1 H and 13 C NMR chemical shift assignments obtained from one-and twodimensional NMR techniques for acridin-9(10H)-ones substituted with (6-X-1,3-benzothiazol-2-yl)amino groups (X D H, NH 2 and NO 2 ). 1 H and 13 C NMR chemical shifts are also reported for the respective aminoacridin-9(10H)-one precursors (Fig.…”

“…In this paper we report the complete 1 H and 13 C NMR chemical shift assignments obtained from one-and twodimensional NMR techniques for acridin-9(10H)-ones substituted with (6-X-1,3-benzothiazol-2-yl)amino groups (X D H, NH 2 and NO 2 ). 1 H and 13 C NMR chemical shifts are also reported for the respective aminoacridin-9(10H)-one precursors (Fig. 1).…”

The Structure ofN‐phenyl‐pyrazoles and Indazoles: Mononitro, Dinitro, and Trinitro Derivatives

“…We have published 40 papers on the title topic between 1959 and 2013; this set continues to be the only systematic study of these compounds . Our publications deal with most of these structures: 1 ; 3 ; 4 ; 5 ; 7 ; 9 ; 10 ; 11 ; 13 ; 14 ; and 15 . We have not studied compounds related to structures 2 (3‐nitro), 6 (3,5‐dinitro), 8 (2‐nitro), and 12 (2‐nitro).…”