Reduction in the incidence of MRSA with use of alcohol-based hand rub solutions and gloves

Matsumoto, Kazuaki; Shigemi, Akari; Yaji, Keiko; Shimodozono, Yoshihiro; Takeda, Yasuo; Ikawa, Kazuro; Morikawa, Norifumi; Miyanohara, Hiroaki; Kawamura, Hideki; Orita, Michiyo; Tokuda, Koichi; Nishi, Junichiro; Yamada, Katsushi

doi:10.1007/s10156-011-0291-5

Cited by 13 publications

(7 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Yoon and colleagues9 described that a proportion of resistance in S. aureus was correlated to penicillin use. Cons for AUDs’ influence, however, claimed that measures against cross infection more influenced the spread of S. aureus than did antimicrobial use 10. However, the factor of former and latter periods did not significantly influence MRSA inpatient ratio in our study.…”

Section: Discussioncontrasting

confidence: 70%

Association between ward-specific antimicrobial use density and methicillin-resistant Staphylococcus aureus surveillance: a 60-month study

Yoshida¹,

Kikuchi²,

Matsubara³

et al. 2013

IDR

View full text Add to dashboard Cite

It is not known whether or not ward-specific antimicrobial use density (AUD) affects the ratio of methicillin-resistant Staphylococcus aureus (MRSA) in culture-positive S. aureus. A 60-month study was attempted to ascertain the association between inpatient MRSA ratio and ward-specific AUDs as well as the former and latter study intervals, specimen types, and ward specialty. During the study, the professionals in infection control regulated the use of broad-spectrum antimicrobials and those for MRSA. By both month and ward, the ratio of inpatients positive for MRSA to those positive for S. aureus was calculated. Factors associated with MRSA ratio included AUDs averaged for the sampling month and its previous month, outpatient MRSA ratio by age, ward specialty, specimen type, and half intervals to represent historical changes. Of a total of 4,245 strains of S. aureus isolated during the 5-year study, 2,232 strains (52.6%) were MRSA. By year, outpatient MRSA ratio at age ≥15 decreased in later years, as did inpatient MRSA ratio. Multivariate analysis for inpatient MRSA ratio revealed a positive risk in AUDs for meropenem (odds ratio [OR] 1.761; 95% confidence interval [CI] 1.761–2.637, P = 0.01), imipenem-cilastatin (OR 1.583; 95% CI 1.087–2.306, P = 0.02), ampicillin-sulbactam (OR 1.623; 95% CI 1.114–2.365, P = 0.01), and minocycline (OR 1.680; CI 1.135–2.487, P = 0.01), respiratory care ward (OR 2.292; 95% CI 1.085–4.841, P = 0.03), and outpatient MRSA ratio (OR 1.536; 95% CI 1.070–2.206, P = 0.02). Use of broad-spectrum antimicrobials, such as meropenem, imipenem-cilastatin, and ampicillin-sulbactam may increase inpatient MRSA ratio. Ward factor should be included in MRSA surveillance because of the possible effect on AUD and considering patients’ backgrounds.

show abstract

Section: Discussioncontrasting

confidence: 70%

Association between ward-specific antimicrobial use density and methicillin-resistant Staphylococcus aureus surveillance: a 60-month study

Yoshida¹,

Kikuchi²,

Matsubara³

et al. 2013

IDR

View full text Add to dashboard Cite

show abstract

“…Nasal application of mupirocin for residents identi ed as having MRSA at the initial admission might be effective for the prevention of MRSA transmission inside an LTCF; however, this should be carefully assessed owing to the high costs as well as the possible increase in MRSA with resistance to mupirocin. [53] Among various prevention strategies, thorough hand hygiene as well as appropriate use of gloves is recommended to maximize de cient medical resources in LTCFs and to reduce excess costs [54,55] This study includes some limitations. First, we did not obtain complete information on the background of residents, such as sex, age, general condition, and medical history owing to the ethics protocol followed; the ethics review board did not grant approval to obtain this information.…”

Section: Discussionmentioning

confidence: 99%

Association Between Length of Residence and Prevalence of Mrsa Colonization Among Residents in Geriatric Long-term Care Facilities

Sasahara

Yoshimura

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: A high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization has been reported among residents in geriatric long-term care facilities (LTCFs). Some studies indicate that MRSA might be imported from hospitals into LTCFs via resident transfer; however, other studies report that high MRSA prevalence might be caused by cross-transmission inside LTCFs. We aimed to assess which factors have a large impact on the high MRSA prevalence among residents of geriatric LTCFs.Methods: We conducted a cohort study among 260 residents of four geriatric LTCFs in Japan. Dividing participants into two cohorts, we separately analyzed (1) the association between prevalence of MRSA carriage and length of LTCF residence (Cohort 1: n=204), and (2) proportion of residents identified as MRSA negative who were initially tested at admission but subsequently identified as positive in secondary testing performed at ≥2 months after their initial test (Cohort 2: n=79).Results: Among 204 residents in Cohort 1, 20 (9.8%) were identified as positive for MRSA. Compared with residents identified as MRSA negative, a larger proportion of MRSA-positive residents had shorter periods of residence from the initial admission (median length of residence: 5.5 vs. 2.8 months), although this difference was not statistically significant (p=0.084). Among 79 residents in Cohort 2, 60 (75.9%) were identified as MRSA negative at the initial testing. Of these 60 residents, only one (1.7%) had subsequent positive conversion in secondary MRSA testing. In contrast, among 19 residents identified as MRSA positive in the initial testing, 10 (52.6%) were negative in secondary testing.Conclusions: The prevalence of MRSA was lower among residents with longer periods of LTCF residence than among those with shorter periods. Furthermore, few residents were found to become MRSA carrier after their initial admission. These findings highlight that MRSA in LTCFs is most likely to be associated with resident transfer rather than spread via cross-transmission inside LTCFs.

show abstract

“…Similarly to patients undergoing cardiac surgery, patients scheduled for clean vascular surgery should be screened if they present with chronic skin lesions or if they come from intensive care units, long- or mid-term care facilities, or departments with a high prevalence of MRSA [3,20,21]. …”

Section: Discussionmentioning

confidence: 99%

“…To reduce contact-based bacterial transmission all HCWs should apply basic infection control practices and comply with isolation measures for identified MRSA carriers [21,22]. …”

Section: Discussionmentioning

confidence: 99%

The Screening of Methicillin-Resistant <b><i>Staphylococcus aureus</i></b> in Vascular Surgery Patients: A Comparison of Molecular Testing and Broth-Enriched Culture

Fiolić

Bošnjak²,

Šnajdar³

et al. 2012

Chemotherapy

View full text Add to dashboard Cite

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a major global health care-associated pathogen. This study sought to examine the prevalence of MRSA in patients who were admitted to a vascular surgery ward during a 3-month period. Methods: MRSA screening was accomplished through the acquisition of nasal, throat and perineal swabs. These swabs were placed in tryptic soy broth that had been supplemented with 6.5% NaCl and incubated for 24 h. The resulting isolates were subcultured on agar plates containing 5% sheep blood. The BD GeneOhm MRSA assay for screening swabs was performed in accordance with the manufacturer’s instructions. Results: A total of 58 patients were included in the study and swabs from 232 sites were obtained during the sampling period. MRSA was detected in 33 samples of 12 patients during the study period; thus, there was a 20.6% prevalence of patients who were recognized as MRSA carriers. There were discrepancies between the results of classical bacteriological screening and molecular MRSA detection methods in 8 of the patients. Conclusions: Nasal, throat and perineal MRSA screening can detect the carriage of this pathogen and allow for the timely use of appropriate infection control measures. The choice of screening techniques poses a challenge; it has been demonstrated that molecular detection methods should be performed with great sensitivity, specificity and, most importantly, speed. The cost of the PCR screening method is the only disadvantage of this approach.

show abstract

Reduction in the incidence of MRSA with use of alcohol-based hand rub solutions and gloves

Cited by 13 publications

References 15 publications

Association between ward-specific antimicrobial use density and methicillin-resistant Staphylococcus aureus surveillance: a 60-month study

Association between ward-specific antimicrobial use density and methicillin-resistant Staphylococcus aureus surveillance: a 60-month study

Association Between Length of Residence and Prevalence of Mrsa Colonization Among Residents in Geriatric Long-term Care Facilities

The Screening of Methicillin-Resistant <b><i>Staphylococcus aureus</i></b> in Vascular Surgery Patients: A Comparison of Molecular Testing and Broth-Enriched Culture

Contact Info

Product

Resources

About