Reduction of allergic reactions in patients undergoing long-term hemodialysis

Cavaillon, Jean‐Marc; Poignet, Jean-Louis; Fitting, Catherine; Delons, S; David, B.

doi:10.1016/0091-6749(93)90180-n

Cited by 4 publications

(3 citation statements)

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“…Improved degassing techniques, thoroughly rinsing new dialysers and tubing, and replacing EtO by steam or gamma radiation to sterilize dialysers, may help (but not always, e.g. EtO originating from the dialyser potting) circumvent this problem (31–33).…”

Section: Aetiologymentioning

confidence: 99%

Haemodialysis‐associated anaphylactic and anaphylactoid reactions

Ebo

Bosmans²,

Couttenye³

et al. 2006

Allergy

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Anaphylactic and anaphylactoid reactions related to haemodialysis have been increasingly described for almost 3 decades. The majority of these cases used to occur with ethylene oxide sterilized, and complement‐activating cellulose membranes. However, a considerable number of publications have focused on polyacrylonitrile AN69® high flux membranes, angiotensin converting enzyme inhibitors and iron as other important causes of potentially severe haemodialysis‐related anaphylactoid reactions. Clinical manifestations vary considerably and generally do not allow differentiation between IgE‐mediated anaphylaxis and anaphylactoid reactions (e.g. from nonspecific mediator release). Successful management of these patients requires multidisciplinary approach and involves prompt recognition and treatment by the attending physician, and identification of the offending agent(s) with subsequent avoidance of the incriminated compound(s). This review focuses on some major causes of anaphylactoid and anaphylactic reactions during haemodialysis. Special consideration is given to the therapeutic and diagnostic approach.

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Section: Aetiologymentioning

confidence: 99%

Haemodialysis‐associated anaphylactic and anaphylactoid reactions

Ebo

Bosmans²,

Couttenye³

et al. 2006

Allergy

View full text Add to dashboard Cite

show abstract

“…Ethylene oxide is a surface disinfectant commonly used to sterilize heat-sensitive medical equipment, such as the procedural kits used in ECP [4]. Acute hypersensitivity reactions have been observed in patients undergoing hemodialysis using ethylene [5,8,9]. In one clinical study, the replacement of ethylene oxide-sterilized material with gamma-irradiated material resulted in clinical improvement of symptoms within three months and reduced levels of IgE antibodies to ethylene oxide [9].…”

Section: Introductionmentioning

confidence: 99%

“…Acute hypersensitivity reactions have been observed in patients undergoing hemodialysis using ethylene [5,8,9]. In one clinical study, the replacement of ethylene oxide-sterilized material with gamma-irradiated material resulted in clinical improvement of symptoms within three months and reduced levels of IgE antibodies to ethylene oxide [9]. Moreover, there has been a reported case of a patient who developed generalized, severe pruritus while undergoing ECP for CTCL [4].…”

Section: Introductionmentioning

confidence: 99%