“…As enamel demineralization and the formation of white-spot lesions occur so rapidly [20], within only a few weeks [17], prevention strategies focus primarily on the application of fluoridereleasing varnishes [6,23], fluoride-releasing bonding materials or cements [7,8], on the repeated application of highly concentrated fluoride gels [29] or daily rinsing [4,10,13,16] to prevent enamel loss by demineralization. Chlorhexidine applications such as the chlorhexidine-thymol varnish Cervitec (Ivoclar Vivadent, Schaan, Liechtenstein) are also considered helpful in preventing white-spot lesions, namely by lowering the level of mutans streptococci [22].…”