Reduction of chlorhexidine-induced chemical burns in extremely preterm infants by using 0.2% chlorhexidine-acetate as a skin disinfectant

Janssen, Lisanne M. A.; Tostmann, Alma; Hopman, Joost; Liem, Kian D.

doi:10.1016/j.jpeds.2018.01.049

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…Chlorhexidine solutions are effective skin cleansing agents, but they can cause chemical burns in preterm infants when used at relatively high concentrations [66,67]. There is evidence supporting the use of 2% chlorhexidine gluconate over 0.5% chlorhexidine gluconate in 70% alcohol for skin disinfection before vascular access insertion as it is linked to fewer skin injuries and comparable rates of central-line-associated bloodstream infections [68,69]. Therefore, the volume and the duration of antiseptic skin cleansing solutions should be approached judiciously, as regular use can delay skin healing, and their use should be focused on procedures and infection prevention [70].…”

Section: Emollients and Skin Antisepsismentioning

confidence: 99%

Thermoregulation, incubator humidity, and skincare practices in appropriate for gestational age ultra-low birth weight infants: need for more evidence

Mishra,

August,

Walker

et al. 2024

World J Pediatr

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Background Although not universal, active care is being offered to infants weighing < 500 g at birth, referred to as ultra-low birth weight (ULBW) infants appropriate for gestational age. These infants have the greatest risk of dying or developing major morbidities. ULBW infants face challenges related to fluid and heat loss as well as skin injury in the initial days of life from extreme anatomical and physiological immaturity of the skin. Although there is an emerging literature on the outcomes of ULBW infants, there is a paucity of evidence to inform practice guidelines for delivering optimal care to this cohort of infants. Data sources A comprehensive review of the literature was performed using the PubMed and Embase databases. Searched keywords included “thermoregulation or body temperature regulation”, “incubator humidity”, “skin care”, “infant, extremely low birth weight” and “ultra-low birth weight infants”. Results Evidences for thermoregulation, incubator humidity, and skincare practices are available for preterm infants weighing < 1500 g at birth but not specifically for ULBW infants. Studies on thermoregulation, incubator humidity, or skincare practices had a small sample size and did not include a sub-group analysis for ULBW infants. Current practice recommendations in ULBW infants are adopted from research in very and/or extremely low birth weight infants. Conclusions This narrative review focuses on challenges in thermoregulation, incubator humidity, and skincare practices in ULBW infants, highlights current research gaps and suggests potential developments for informing practices for improving health outcomes in ULBW infants.

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Section: Emollients and Skin Antisepsismentioning

confidence: 99%

Thermoregulation, incubator humidity, and skincare practices in appropriate for gestational age ultra-low birth weight infants: need for more evidence

Mishra,

August,

Walker

et al. 2024

World J Pediatr

View full text Add to dashboard Cite

show abstract

“…For skin disinfection prior to insertion of vascular accesses there is evidence to support the use of 2% chlorhexidine gluconate instead of 0.5% chlorhexidine gluconate in 70% alcohol, as it is associated with fewer skin lesions and similar rates of central-line associated bloodstream infections [46,47].…”

Section: Skin Disinfectionmentioning

confidence: 99%

Nursing care of infants born extremely preterm

Karlsson

Blomqvist

Ågren

2022

Seminars in Fetal and Neonatal Medicine

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Skin Care for the Extremely Low-Birthweight Infant

et al. 2023

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Extremely low-birthweight (ELBW) infants are at increased risk for infection because the innate immune function of their skin is underdeveloped as they lack a competent epidermal barrier. Thus, neonatal clinicians need to pay careful attention to skin care practices, particularly for periviable infants. In this review, we describe the challenges of skin care in ELBW infants and summarize strategies to prevent skin injury, minimize damage when it occurs, and enhance cutaneous innate immunity.

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Reduction of chlorhexidine-induced chemical burns in extremely preterm infants by using 0.2% chlorhexidine-acetate as a skin disinfectant

Cited by 4 publications

References 4 publications

Thermoregulation, incubator humidity, and skincare practices in appropriate for gestational age ultra-low birth weight infants: need for more evidence

Thermoregulation, incubator humidity, and skincare practices in appropriate for gestational age ultra-low birth weight infants: need for more evidence

Nursing care of infants born extremely preterm

Skin Care for the Extremely Low-Birthweight Infant

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