Reduction of daily-use parabens and phthalates reverses accumulation of cancer-associated phenotypes within disease-free breast tissue of study subjects

Beauty Beware: Associations between Perceptions of Harm and Safer Hair-Product-Purchasing Behaviors in a Cross-Sectional Study of Adults Affiliated with a University in the Northeast

“…In another study [15], which examined the impact of an intervention on adolescent product use, researchers found that choosing products labeled "free of phthalates, parabens, triclosan, and benzophenone-3" was associated with lower urinary concentrations of these EDCs. Moreover, a separate study showed that using paraben-free and phthalate-free products over 28 days was associated with both reduced urinary concentrations of these EDCs and a reversal of cancer-associated phenotypes at the cellular and molecular level in healthy breast tissues (namely, transcriptional shifts in the expression of known cancer-associated genes and shifts toward the normalization of estradiol-modulated pathways) [16]. While these studies identified associations between product use and urinary concentrations of EDCs or cancer-associated phenotypes, they did not examine what factors motivate these safer consumer behaviors.…”