Reduction of Diarrhea-associated Hospitalizations Among Children Aged &lt;5 Years in Panama Following the Introduction of Rotavirus Vaccine

Moltó, Yadira; Cortes, Jennifer; Oliveira, Lúcia Helena de; Mike, A.; Solis, Itzel; Suman, Onix Marisel S. de; Coronado, Luis; Patel, Manish; Parashar, Umesh D.; Cortese, Margaret M.

doi:10.1097/inf.0b013e3181fefc68

Cited by 73 publications

(42 citation statements)

References 12 publications

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“…The fall in hospital admissions for diarrhoea noted in Rwanda is similar to decreases recorded in Brazil, Mexico, and Panama, and the decreased hospital admissions for rotavirus are similar to those reported in Brazil and El Salvador after the implementation of rotavirus vaccine in these countries. 7,[26][27][28][29][30] We noted a greater reduction in the number of hospital admissions for diarrhoea in 2013 compared with 2014. This phenomenon of alternating years of larger and smaller reductions has been recorded over 7 postintroduction years in the USA and is probably the result of the accumulation of susceptible children over successive seasons resulting in increased transmission.…”

Section: Discussionmentioning

confidence: 94%

Effect of pentavalent rotavirus vaccine introduction on hospital admissions for diarrhoea and rotavirus in children in Rwanda: a time-series analysis

Ngabo

Tate

Gatera

et al. 2016

The Lancet Global Health

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SummaryBackground In May, 2012, Rwanda became the fi rst low-income African country to introduce pentavalent rotavirus vaccine into its routine national immunisation programme. Although the potential health benefi ts of rotavirus vaccination are huge in low-income African countries that account for more than half the global deaths from rotavirus, concerns remain about the performance of oral rotavirus vaccines in these challenging settings.

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Section: Discussionmentioning

confidence: 94%

Effect of pentavalent rotavirus vaccine introduction on hospital admissions for diarrhoea and rotavirus in children in Rwanda: a time-series analysis

Ngabo

Tate

Gatera

et al. 2016

The Lancet Global Health

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“…1 In addition to the benefit of ORS usage, improvement may be due to regional improvements in education and sanitation, 17 diarrheal disease or cholera control programs, 18 and the introduction of rotavirus vaccine, which has effectively reduced rotavirus-associated diarrhea incidence and pediatric-associated hospitalization. 19,20 Although these successes are to be applauded, our prevalence maps highlight areas where prevention efforts should be redoubled or new interventions undertaken.…”

Section: Discussionmentioning

confidence: 99%

Diarrhea Prevalence, Care, and Risk Factors Among Poor Children Under 5 Years of Age in Mesoamerica

Colombara¹,

Hernández²,

McNellan³

et al. 2016

The American Society of Tropical Medicine and Hygiene

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Abstract. Care practices and risk factors for diarrhea among impoverished communities across Mesoamerica are unknown. Using Salud Mesoamérica Initiative baseline data, collected 2011-2013, we assessed the prevalence of diarrhea, adherence to evidence-based treatment guidelines, and potential diarrhea correlates in poor and indigenous communities across Mesoamerica. This study surveyed 14,500 children under 5 years of age in poor areas of El Salvador, Guatemala, Mexico (Chiapas State), Nicaragua, and Panama. We compared diarrhea prevalence and treatment modalities using χ 2 tests and used multivariable Poisson regression models to calculate adjusted risk ratios (aRRs) and 95% confidence intervals (CIs) for potential correlates of diarrhea. The 2-week point prevalence of diarrhea was 13% overall, with significant differences between countries (P < 0.05). Approximately one-third of diarrheal children were given oral rehydration solution and less than 3% were given zinc. Approximately 18% were given much less to drink than usual or nothing to drink at all. Antimotility medication was given to 17% of diarrheal children, while antibiotics were inappropriately given to 36%. In a multivariable regression model, compared with children 0-5 months, those 6-23 months had a 49% increased risk for diarrhea (aRR = 1.49, 95% CI = 1.15, 1.95). Our results call for programs to examine and remedy low adherence to evidence-based treatment guidelines.

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“…The safety, effectiveness and impact of rotavirus vaccine introduction in the decrease of severe gastroenteritis, hospitalizations, and deaths in some LA countries was discussed, including Mexico, El Salvador, Brazil and Panama [6][7][8][9]. Despite the worldwide and local beneficial evidence, some LA countries have still not introduced it universally due to economical reasons, among others.…”

mentioning

confidence: 99%

Vaccine-preventable diseases and their impact on Latin American children

Ulloa‐Gutiérrez

Miño²,

Odio³

et al. 2011

Expert Review of Vaccines

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Reduction of Diarrhea-associated Hospitalizations Among Children Aged <5 Years in Panama Following the Introduction of Rotavirus Vaccine

Abstract: RV1 appears to have had a substantial impact on diarrhea-associated hospitalizations among young children in Panama.

Cited by 73 publications

References 12 publications

Effect of pentavalent rotavirus vaccine introduction on hospital admissions for diarrhoea and rotavirus in children in Rwanda: a time-series analysis

Effect of pentavalent rotavirus vaccine introduction on hospital admissions for diarrhoea and rotavirus in children in Rwanda: a time-series analysis

Diarrhea Prevalence, Care, and Risk Factors Among Poor Children Under 5 Years of Age in Mesoamerica

Vaccine-preventable diseases and their impact on Latin American children

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