Reduction of Framingham BMI score after rapid weight loss in severely obese subjects undergoing sleeve gastrectomy: a single institution experience

Abstract

Sleeve gastrectomy has demonstrated to be an effective method of treatment for obesity. Our results suggest that rapid weight loss after LSG has a positive impact in the reduction of the 10-year cardiovascular disease risk. Further prospective studies may be needed to better assess these findings.

Impact of Bariatric Surgery on Cardiovascular Risk Reduction in Korean Obese Patients

“…This study demonstrated that bariatric surgery reduces the CVD risk, as significant improvement of all CVD risk scores were observed after surgery. This result is concordant with that of other studies that used FRS or PCE [13][14][15].…”

“…However, the FRS or PCE scores at baseline and after surgery in this study seemed to be lower than those in previous studies. The FRS at baseline and 1 year after surgery in our study showed a mean value of 10.3% and 4.1% respectively, whereas the FRS was 26.6% and 16.7%, respectively, in one study [15] and 34.5% and 15.5%, respectively, in another study [13]. With respect to PCE, our data (5.2% and 2.7% at baseline and 1 year after surgery, respectively) were lower than those of a previous study (11.6 and 7.8, respectively) [14].…”

“…Second, there were differences in the calculation methods of the risk scores. We used the lipid-based FRS for the prediction of CVD; however, other studies used the BMI-based FRS, which could produce higher estimates than the lipid-based FRS in obese patients [13,15]. However, a similar relative risk reduction was observed between this study (39.6% in FRS and 48.5% in PCE) and other studies (37.2%, 37.5%, 55.1% in FRS [13][14][15] and 32.8% in PCE [14]), although the absolute risk reduction in this study was lower than that in other studies.…”

“…Heart Association (ACC/AHA), are generally used to quantitatively assess the 10-year CVD risk [10,11]. Several studies have addressed the efficacy of bariatric surgery in reducing the CVD risk based on either the FRS or PCE, or both [12][13][14][15]. However, some investigators demonstrated that FRS and PCE can overestimate the risk in populations in Europe and Asia including Korea [16][17][18][19][20][21].…”

“…In addition, studies on which kind of bariatric surgery would be more beneficial in improving the CVD score are rare. Several studies reported that laparoscopic Roux-en Y gastric bypass (LRYGB), laparoscopic sleeve gastrectomy (LSG), and laparoscopic adjustable gastric banding reduced the CVD risk score; however, most of them were noncomparative studies [12,[24][25][26] and only few studies directly compared LSG and LRYGB [13][14][15]27].…”