Reduction of surface roughness of a laminin–apatite composite coating via inhibitory effect of magnesium ions on apatite crystal growth

Laser-assisted biomineralization on human dentin for tooth surface functionalization

“…[10,11]). In biomimetic processes, the nano-and micro-structures, composition, and even the biological functions of the resulting CaP coatings can be controlled by fine-tuning the reaction conditions [7,8,12,13].…”

Control of Surface Topography in Biomimetic Calcium Phosphate Coatings

“…In view of the above, it would be beneficial to control the surface porosity and complexity of biomimetic CaP coatings. However, to the best of our knowledge, only a few studies have attempted to control surface topography of apatite coatings by altering Mg 2+ levels or pH of SBF. , In the present study, apatite coatings were deposited on functionalized polycaprolactone (PCL) films by incubation in supersaturated SBF solutions. PCL is a biocompatible and biodegradable polymer having a relatively slow rate of degradation, making it an ideal scaffold for bone tissue engineering applications, where a slowly degrading material is desired. , Our objective was to investigate the effect of ionic concentration, level of crystal growth inhibitors (Mg 2+ , HCO 3 – ), and soaking time on the surface properties of the resulting CaP coatings deposited on PCL.…”

Silicate–apatite composite layers on external fixation rods and in vitro evaluation using fibroblast and osteoblast

“…Complications in external fixation pins, such as pin loosening and pin tract infections, arise primarily from mechanical instability in the skin‐ and bone‐pin interfaces 6, 7, 39. Clinically, an improvement in the bone‐external fixation pins interface strength and the prevention of pin tract infection are important in the course of treatment by external fixation.…”

“…Clinically, an improvement in the bone‐external fixation pins interface strength and the prevention of pin tract infection are important in the course of treatment by external fixation. Improvements in bone‐pin interface strength and infection resistance lead to patients' early recovery 6, 7, 39. Therefore, the present silicate–apatite composite layers, which caused increased fibroblastic proliferation and osteoblastic proliferation and differentiation in vitro , are promising as coating layers on external fixation pins for decreasing the pin tract infection rate in vivo .…”

“…Bacterial infection that occurs at a high rate in external fixation pins has been attributed to the pin tract that the pins provide between the skin and underlying soft tissue and bone 4. Recently, bacterial infection was found to be effectively prevented by increasing the bonding ability of external fixations to skin and bone tissue 5–7. By forming an apatite layer on the external fixator, the enhancement of soft tissue and bone tissue regeneration around the external fixation site is a very effective and promising way to prevent bacterial infections 5, 7–12…”