Reduction of the surgical excision rate in benign breast disease using fine needle aspiration cytology with immediate reporting

Abstract

Patients attending a breast clinic in two different periods were studied. In the first period fine needle aspiration cytology (FNAC) was not available and in the second it was used on all discrete solid breast lumps and reported immediately in the clinic. With the use of FNAC the overall surgical excision rate for discrete solid lumps was reduced from 83 per cent to 41 per cent and the excision rate in patients with benign disease was reduced from 74 per cent to 23 per cent (P less than 0.001). All patients with breast cancer in the second period had malignant cytology and no patient with benign or acellular cytology has been shown, after a minimum follow-up period of 18 months, to have breast cancer. Using FNAC with immediate reporting, the number of operations performed in patients with benign breast disease can be safely reduced.

The diagnostic value of on‐site cytopathological evaluation and cell block preparation in fine‐needle aspiration cytology of liver masses

“…The impact of on‐site cytopathological examination of breast, thyroid, head and neck masses, lung lesions, and lymph nodes has been well established, 27,29,31–34 but few studies have focused on this issue for the diagnosis of liver masses 7,8,27,35 . In our study, the sensitivity of preliminary diagnosis, CS, and combined approach in the diagnosis of liver masses were 92.8%, 92.8%, and 93.5%, respectively.…”

Bivariate Random Effects Meta-Analysis of ROC Curves

“…FNAC provides a nonoperative way of obtaining cells for establishment of the nature of a breast lump and therefore plays a pivotal role in the preoperative diagnostic process. [16][17][18][19] The sensitivity and specificity of FNAC were determined for each study. Sensitivity was defined as the probability of a malignant or suspect test result in patients with cancer.…”

Fine Needle Aspiration Cytology of Palpable Breast Lesions

“…Among young women who have clinically benign lumps, who are anxious to avoid scars or who have had recurrent fibroadenomas, some can be safely followed‐up without operative intervention after a benign cytology report 10 . Under circumstances where surgery is going to be performed, the surgeon can excise less or no normal tissue surrounding the lesion, which is likely to produce a better cosmetic result.…”