To the Editor: Recent years have seen Botulinum Neurotoxin (BoNT) injections emerge as a treatment option in the management of muscle spasticity. Spasticity is observed in many upper motor neuron problems but stroke and cerebral palsy are two of the more common conditions for which BoNT has been used to reduce muscle spasticity, release contractures and improve function [1]. Spasticity in the hand and forearm can be particularly problematic due to the prominent role of the upper extremity in activities of daily living [2]. BoNT exerts its effect at the neuromuscular junction to block acetylcholine release into the synaptic cleft and cause muscle relaxation [3]. Its use is limited by the ability of axons to regenerate at the neuromuscular junction; hence the effects of toxin injections are only temporary. There are also limitations in cases of prolonged muscular contracture which result in postural abnormalities and commonly require corrective surgery. Toxin use is often used as an alternative to tendon lengthening or tendon transfer; however our centre is now implementing a number of novel uses for BoNT injections with a view to improving outcomes in our cerebral palsy patients. We report a 16 year old patient with cerebral palsy who underwent a left flexor carpi radialis (FCR) to extensor carpi radialis longus (ECRL) tendon transfer with release of flexor digitorum superficialis (FDS) and flexor pollicis longus (FPL). Ultrasound guided BoNT injections were administered 2 weeks preoperatively to FCR, FDS, FDP, and FPL. The 2 week delay allowed the BoNT to exert its full effect and achieve a maximum preoperative reduction in muscle tension. We typically use doses of 50 units BoNT per muscle. Our main finding is that BoNT injections can be valuable when used in conjunction with tendon lengthening and tendon transfer techniques, as a combination of surgery and injections produce a synergistic effect. With regards to tendon lengthening in FDS and FPL, preoperative reduction in muscle tension made achievement of optimum tendon length and hand position a more straightforward process. Reduced muscle tension makes the surgeon's task easier and leads to a better postoperative result. This finding supports results in animal models where manipulation of the muscle-tendon unit was made easier by preoperative injection of BoNT [4]. The benefits of this technique are also seen in tendon transfer. Firstly, reducing tension in the transferred FCR tendon allows for an easier transfer, attachment and attainment of an optimum hand position. Secondly, by reducing tension on antagonistic muscles (wrist flexors FDS and FDP), the ability to achieve an optimum hand position is more straightforward and, theoretically, the risk of post operative failure is reduced as the antagonistic force across the transferred tension is less. At present, this technique has been used on a number of patients at our centre and so far the results are promising with the surgeon noting the ease with which a good hand position is achieved intraoperatively co...