Reference values and clinical predictors of bone strength for HR-pQCT-based distal radius and tibia strength assessments in women and men

Reference data and calculators for second-generation HR-pQCT measures of the radius and tibia at anatomically standardized regions in White adults

“…A number of studies have provided reference data for HR-pQCT outcomes [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. These provide a means of expressing an individual's outcomes relative to peers, including adolescents and young adults [6,8], and adults from a range of racial and ethnic backgrounds [3-5, 7, 9-17].…”

High-impact exercise stimulated localised adaptation of microarchitecture across distal tibia in postmenopausal women

“…Regionspecific changes in cortical bone were found at the tibial shaft as a result of physical activity [4], and local changes in cortical and trabecular bone mineral content (BMC) were demonstrated at the proximal femur, using quantitative computed tomography (QCT) in older men [5]. Trabecular microarchitecture is another determinant of bone strength [6] [7].…”

Homogenized finite element analysis of distal tibia sections: Achievements and limitations

“…The individuals, who voluntarily donated their bodies for anatomical education and research were 64 to 93 years old at death, with a mean age (± standard deviation) of 82 ± 10 years. Following thawing, the tibiae were scanned using HR-pQCT (XCT II, Scanco Medical, Switzerland) with an in-house protocol ( Stuck et al, 2020 ; Schenk et al, 2020 ) defined to scan ultradistal sections of about 30.6 mm starting from the cortical bone forming the inferior articular surface of the tibia. The scanned section was then cut out and manually lapped to obtain flat and parallel surfaces.…”