Refill adherence for patients with asthma and COPD: comparison of a pharmacy record database with manually collected repeat prescriptions

Krigsman, Kristin; Nilsson, J. Lars G.; Ring, Lena

doi:10.1002/pds.1321

Cited by 71 publications

(51 citation statements)

References 21 publications

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“…5,6 A strength of our study is that we had information on both presence of asthma and lung function. On the other hand, the study was limited by the fact that we had only prebronchodilator pulmonary function test values.…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, most studies have relied only on pharmaceutical databases, and have had limited clinical information. 5,6 As a consequence, most knowledge on use and adherence in relation to clinical information such as severity of COPD comes from randomized controlled trials. 7 There is a need for population-based studies on use and adherence to investigate whether real-life treatment of COPD could be improved.…”

Section: What Is the Major Question?mentioning

confidence: 99%

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Low Use and Adherence to Maintenance Medication in Chronic Obstructive Pulmonary Disease in the General Population

et al. 2014

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OBJECTIVE:We tested the hypothesis that use of and adherence to maintenance medication is low among individuals in the general population who have chronic obstructive pulmonary disease (COPD) , even in cases of severe and very severe COPD. DESIGN AND PARTICIPANTS: We identified 5,812 individuals with COPD from the Copenhagen General Population Study, and classified them according to the Global Initiative for Obstructive Lung Disease (GOLD) airflow limitation grades 1-4. Dispensing of fixed-dose combinations of inhaled corticosteroids with long-acting beta 2 -agonists, long-acting anti-cholinergics, or long-acting beta 2 -agonists was identified in a nationwide registry. Use of medication was defined as medication dispensed during a one-year period , and adherence was calculated from dosages available in one year. KEY RESULTS: Use of fixed-dose combinations of inhaled corticosteroids with long-acting beta 2 -agonists varied from 2 % to 61 % (p<0.001, test for trend), long-acting anti-cholinergics varied from 0.4 % to 36 % (p<0.001), and long-acting beta 2 -agonists varied from 0.3 % to 11 % (p<0.001. Among utilizers of these medications, adherence varied from 29 % to 56 % (p<0.001, test for trend) across GOLD 1-4 for fixed-dose combinations of inhaled corticosteroids with long-acting beta 2 -agonists, from 51 % to 68 % (p=0.11) for long-acting anti-cholinergics, and from 25 to 62 % (p=0.01) for long-acting beta 2 -agonists. CONCLUSIONS: Use of and adherence to maintenance medication for COPD in the general population was associated with the severity of COPD as defined by GOLD, but even in severe and very severe COPD, use and adherence was low.

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Section: Discussionmentioning

confidence: 99%

Section: What Is the Major Question?mentioning

confidence: 99%

Low Use and Adherence to Maintenance Medication in Chronic Obstructive Pulmonary Disease in the General Population

et al. 2014

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“…The cost of nonadherence by patients with chronic diseases is estimated to be $300 billion/y in the United States. 12 According to previous research, the adherence rate of subjects with COPD is Ͼ 50% [13][14][15][16][17][18] as opposed to 30 -70% in subjects with asthma. 19 Patient adherence tends to be lower in the evening and declines over time.…”

Section: Problems With Patient Education and Adherence To Aerosol Thementioning

confidence: 99%

Patient Education and Adherence to Aerosol Therapy

Ari

2015

Respir Care

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SummaryNonadherence to prescribed medications results in disease instability and poor clinical control, with increases in hospital admissions, emergency room visits, school/work absenteeism, morbidity, and mortality. Poor patient adherence to therapy can be due to lack of cognition, competence, or contrivance. Patients who have not been trained or fail to understand use of drug and device combinations (cognition) often do not have the ability to use an aerosol device correctly (competence). Many patients have the competence to use the device correctly and know why they should RESPIRATORY CARE • JUNE 2015 VOL 60 NO 6 941 use the device in the way they were taught; however, they still contrive to use it in an ineffective and suboptimal manner that reduces its efficiency and effectiveness. Ensuring effective aerosol therapy and optimizing its role in disease management involve not only delivery of aerosolized medications to the lungs, but also understanding why, when, and how to use the medications, competence to use the device, motivation to adhere to therapy, and not contriving to use the device in a way that will prevent effective drug delivery. This paper explains some of the problems with patient education and adherence to aerosol therapy and suggests strategies to evaluate, monitor, and improve patient adherence effectively in primary care. Factors affecting patient adherence to prescribed medications, effective educational interventions, and strategies to promote patient adherence to aerosol therapy are also discussed.

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“…Less than perfect adherence to ICS appears to account for the majority of asthma-related hospitalizations (4,5). The reported adherence rate of COPD and asthma patients is about 50% and 30-70%, respectively (6)(7)(8)(9)(10)(11).…”

Section: Introductionmentioning

confidence: 99%

Factors affecting satisfaction with education program for chronic airway disease in primary care settings

et al. 2017

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Background: A well-organized education program improved the patients' knowledge about their disease, inhaler technique and quality of life in asthma and chronic obstructive pulmonary disease (COPD) patients.The effectiveness of the education program can be evaluated by assessing patients' satisfaction with the education program as well. In this study, we compared the patients' satisfaction with education program between COPD and asthma patients.Methods: A total of 284 asthma and COPD patients were enrolled. Three educational visits were conducted at 2-week intervals. On the first visit, we taught the patients about their diseases and the proper inhaler technique. On the second visit, non-pharmacologic treatments and action plans for acute exacerbation were introduced. On the final appointment, we summarized the educational concepts covered in the two prior visits. After the education program, the patients were assessed for their quality of life, knowledge of chronic airways disease, and satisfaction with the education program, using a structured questionnaire.Results: After the education program, 99.3% of the asthma patients knew much more about their disease and 96.8% agreed that education from the hospital is needed. For COPD patients, 94.8% felt more informed about their disease and 95.7% agreed that education from the hospital is needed. However, 17.1% of asthma patients and 13.5% of COPD patients disagreed to paying an additional fee for the education program.Finally, the knowledge improvement was linked to patient satisfaction with the education program. Conclusions:The improvement in self-knowledge about their disease was linked to their satisfaction with the education program. However, costs associated with the program could limit its accessibility to the patients. The patient education program is a self-management intervention to improve the lives of patients with asthma and COPD. Thus, a policy to reduce the economic burden of the patients should be considered to disseminate the education program in primary care clinics.

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Refill adherence for patients with asthma and COPD: comparison of a pharmacy record database with manually collected repeat prescriptions

Abstract: Refill adherence determined from manually collected repeat prescriptions and from a pharmacy record database did not differ for a 1-year period. Four-year data might give a better overview of patients' refill adherence than 1-year data.

Cited by 71 publications

References 21 publications

Low Use and Adherence to Maintenance Medication in Chronic Obstructive Pulmonary Disease in the General Population

Low Use and Adherence to Maintenance Medication in Chronic Obstructive Pulmonary Disease in the General Population

Patient Education and Adherence to Aerosol Therapy

Factors affecting satisfaction with education program for chronic airway disease in primary care settings

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