Refining the rheological characteristics of high drug loading ointment via SDS and machine learning
Xilong Qian,
Kewei Wang,
Yulu Ma
et al.
Abstract:This paper presents an optimized preparation process for external ointment using the Definitive Screening Design (DSD) method. The ointment is a Traditional Chinese Medicine (TCM) formula developed by Professor WYH, a renowned TCM practitioner in Jiangsu Province, China, known for its proven clinical efficacy. In this study, a stepwise regression model was employed to analyze the relationship between key process factors (such as mixing speed and time) and rheological parameters. Machine learning techniques, in… Show more
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