Reflectance Confocal Microscopy of the Yellow Dot Pattern in Alopecia Areata

Ardigò, Marco; Tosti, Antonella; Cameli, Norma; Vincenzi, Colombina; Misciali, Cosimo; Berardesca, Enzo

doi:10.1001/archdermatol.2010.288

Cited by 44 publications

(47 citation statements)

References 10 publications

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“…These dots appear as small (0.2~0.3 mm) WD distributed regularly in the interfollicular scalp, dispersed across the mosaic pigmented network. They have been correlated with the acrosyringeal and follicular openings10,21. In our study, we saw both these regular pinpoint WD between the HCPP together with irregularly distributed white areas.…”

Section: Discussionsupporting

confidence: 69%

Scalp Dermatoscopic Findings in Androgenetic Alopecia and Their Relations with Disease Severity

Kibar¹,

Aktan

Bilgin

2014

Ann Dermatol

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BackgroundClinicians are searching for new methods to diagnose and predict the course of androgenetic alopecia noninvasively.ObjectiveOur aim is to evaluate trichoscopic findings and their relations with disease severity in androgenetic alopecia.MethodsThe videodermatoscopic findings of 143 female and 63 male patients with androgenetic alopecia were compared with each other, with those of healthy subjects (n=100), and with those of patients with other nonscarring alopecias (n=208). Mann-Whitney U-test, χ2 analyses, and logistic regression analysis were used for statistical analysis.ResultsNo statistically significant relation was found between trichoscopic findings and severity in male androgenetic alopecia (MAGA) on the basis of the modified Hamilton Norwood scale (among 7 degrees); however, multihair follicular unit and perifollicular pigmentation were related to low severity whereas white dots, honeycomb pattern pigmentation, and brown dots were related to high severity. On the other hand, according to the Ludwig classification, arborizing red lines were related to low severity and brown dots were related to high severity, whereas there was no difference in stages between the Ebling and Olsen classifications in female androgenetic alopecia (FAGA). In the characteristic trichoscopic findings in this study, perifollicular pigmentation was found as a normal feature of the scalp, whereas multihair follicular unit and honeycomb pigment pattern, which were previously considered as normal features, were observed to be related to androgenetic alopecia.ConclusionNo relation was found between MAGA severity and trichoscopic findings, as well as between FAGA severity according to different disease severity classifications and trichoscopic findings.

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Section: Discussionsupporting

confidence: 69%

Scalp Dermatoscopic Findings in Androgenetic Alopecia and Their Relations with Disease Severity

Kibar¹,

Aktan

Bilgin

2014

Ann Dermatol

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“…They have been correlated with the acrosyringeal and follicular openings. 16,17 Fu et al 13 identified dirty dots as a normal finding in the scalps of 10 of 19 healthy children. Dirty dots represent nonmicrobial environmental particles and are easily removed after shampooing.…”

Section: Normal Scalpmentioning

confidence: 99%

Hair and scalp dermatoscopy

Miteva

Tosti

2012

Journal of the American Academy of Dermatology

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284

310

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“…Recent studies have shown that RCM may be a useful auxiliary tool in the diagnosis of hair diseases such as alopecia areata, androgenetic alopecia, or hereditary hair dystrophy, although its superiority over trichoscopy has not yet been demonstrated [34]. Ardigo et al [35] performed an RCM study of stratum spinosum of the epidermis in patients with alopecia areata. The study showed a remarkable decrease of follicular adnexal structures and empty lumina with highly refractile material (Fig.…”

Section: Hair Conditionsmentioning

confidence: 99%

Review paper The use of reflectance confocal microscopy in selected inflammatory skin diseases

Białek-Galas¹,

Wielowieyska-Szybińska²,

Dyduch³

et al. 2015

pjp

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Reflectance confocal microscopy is a modern, non-invasive diagnostic method that enables real-time imaging of the epidermis and upper layers of the dermis with nearly histological precision and high contrast. The application of this technology to skin imaging during the last years has resulted in progress of dermatological diagnosis, providing virtual access to living skin, without the need for conventional histopathology. The presented method potentially has broad application in the diagnosis of skin diseases. This article provides a summary of the latest reports and previous achievements in the field of reflectance confocal microscopy. General characteristics of confocal images in selected inflammatory skin diseases are presented.

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Reflectance Confocal Microscopy of the Yellow Dot Pattern in Alopecia Areata

Cited by 44 publications

References 10 publications

Scalp Dermatoscopic Findings in Androgenetic Alopecia and Their Relations with Disease Severity

Scalp Dermatoscopic Findings in Androgenetic Alopecia and Their Relations with Disease Severity

Hair and scalp dermatoscopy

Review paper The use of reflectance confocal microscopy in selected inflammatory skin diseases

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