The liquid crystal variable retarder (LCVR), as a controllable phase modulator, works in a setting voltage or modulated mode and has been applied in the field of microscopic polarimetry. However, the modulation period of an LCVR is normally limited to dozens to hundreds of milliseconds, which is not suitable for a rapid measurement. Based on this feature, in this work, one rapid measuring strategy was reported. Only two frames were needed for a normalized-intensity-difference microscopic anisotropy measurement. The working principle and instrumentation were presented. For demonstration, a flake of graphene was measured by this method and compared by the reported way. An approximately 30× speed improvement was realized with the clear signal measurement. This proposed method will help a fast in situ characterization of ultrathin films and 2D materials.