BACKGROUND Postpartum pain is one of the most important and prevalent problems in the postpartum period. In this regard, reflexology is a common method to reduce this type of pain in women. Therefore, the present study was conducted to determine the effect of foot reflexology on postpartum pain. METHODS This randomized clinical trial study was conducted on mothers referred to obstetrics and gynaecology ward of Razi Teaching Hospital affiliated to Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran from January to December 2018. A total of 68 women were randomly selected as per the inclusion criteria. Then, the participants were assigned to the intervention (n:34) and control (n:34) groups using a table of random digits. In the test group, reflexology was performed for 10 minutes on each foot in the pituitary points, the solar plexus points, the inner arch of the foot, and the uterine point. In the control group, routine care and other foot massages were performed. Data gathering tool in this study was a demographic questionnaire and pain visual analogue scale (VAS). The severity of pain was recorded immediately after the intervention, followed by 30, 60, 120 minutes, and 6 hours after the intervention. In case of intolerable pain, analgesic was prescribed to the mother until 30 minutes after the intervention. Data were analysed using descriptive statistics methods (mean and standard deviation), independent T-test, Kolmogorov-Smirnov, Chi-square, and Mann-Whitney tests using SPSS software version 22. RESULTS The results showed that after foot reflexology, the mean score of pain intensity and duration were significantly decreased in the intervention group in comparison to control group (p< 0.001). Although the use of analgesic in the control group was at times more than the intervention group, it was not statistically significant (p= 0.1) and the foot reflexology did not reduce the need for analgesic. CONCLUSIONS Based on the findings, foot reflexology is an effective and appropriate method for reducing the severity and duration of postpartum pain.