Reflux rising! A disease in evolution?

Bardhan, Kama D.; Royston, Christine; Nayyar, Anil K.

doi:10.1016/s0016-5085(00)84028-7

Cited by 15 publications

(9 citation statements)

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“…Progressive dysphagia can be an indicator of carcinoma and therefore always necessitates further investigation [2]. GERD, an illness with many clinical facets and multifactorial pathogenesis [3], is consistently increasing in frequency in Western industrialized nations [4,5], with large incidental differences in individual countries [6][7][8][9][10][11]. Asian countries have a relatively lower frequency of GERD [9,12,13].…”

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confidence: 99%

Prevalence of Dysphagia in Patients with Gastroesophageal Reflux in Germany

et al. 2008

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Dysphagia is an alarming symptom that raises the possibility of stricture or malignancy. This study compares the prevalence and severity of dysphagia symptoms in subjects with or without gastroesophageal reflux (GERD). In a population-based study, 500 residents of Cologne between the ages of 20 and 90 years [232 (46%) males and 268 (54%) females] were randomly selected from the city register and sent questionnaires with reflux-related questions. Two hundred sixty-eight replies (54%) were accepted into the study. Of these, 45% were men with a median age of 58 years. The median female age was 54 years. Thirty-four percent of the respondents (n=92) admitted having heartburn symptoms. There was no significant gender-based difference. There was little variation in reflux frequency between individual age groups. Twenty-three (25%) of the 92 respondents with reflux reported symptoms more than twice per week. Forty-five percent of this "reflux" group took medications for their heartburn. Swallowing difficulties, predominantly mild, were reported in 11.3% of the respondents. Dysphagia was significantly increased in the reflux group (28%) versus the normal group (3%) (p<0.001). Sixteen percent of respondents with mild and 65% of those with moderate to severe reflux symptoms reported additional dysphagia symptoms (p<0.001). Swallowing problems are common in patients with GERD. Approximately two thirds of patients with long-term and severe reflux symptoms also have dysphagia symptoms. Dysphagia should always be investigated by a physician.

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confidence: 99%

Prevalence of Dysphagia in Patients with Gastroesophageal Reflux in Germany

et al. 2008

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“…urrent epidemiological trends indicate an inverse relationship in the Western world between the rising incidence of gastrooesophageal reflux disease (GERD) and the decreasing incidence of duodenal ulcer disease as the classical clinical expression of Helicobacter pylori infection as well as of H pylori infection in general. [1][2][3] There is still uncertainty whether epidemiological data reflect a real increase of the incidence and prevalence of GERD, or whether merely a higher awareness and more attention is paid by endoscopists in the detection of erosive oesophagitis. 4 There is no doubt, however, that the incidence of Barrett's carcinoma, which is the most serious consequence of GERD, has shown the steepest increase of all gastrointestinal tumours during past decades.…”

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confidence: 99%

The interplay between Helicobacter pylori, gastro-oesophageal reflux disease, and intestinal metaplasia

Malfertheiner

Peitz²

2005

Gut

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“…The analysis of both samples showed that the telephone hotline was used mainly by people who had had their symptoms for a long time and had already been in medical care. The chosen Einleitung Die Refluxkrankheit der Speiseröhre (gastroösophageale Refluxkrankheit = GERD) stellt eine der häufigsten Erkrankungen des Gastrointestinaltrakts mit einer deutlichen Zunahme der Inzidenz in den letzten Jahrzehnten dar [1][2][3]. Dabei wird immer deutlicher, dass die Refluxkrankheit nicht nur eine Befindlichkeitsstörung mit deutlich eingeschränkter Lebensqualität darstellt, sondern eine ernst zu nehmende Erkrankung mit einem breiten Spektrum an Symptomen, Komplikationen und Folgeerkrankungen mit Bedeutung für zahlreiche Fachdisziplinen auch außerhalb der Gastroenterologie ist [4].…”

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Sozialepidemiologische Analyse von Informationsquellen und medizinischer Versorgung einer Subpopulation von Teilnehmerinnen und Teilnehmern einer bundesweiten Informationskampagne „Alarmzeichen Sodbrennen”

Weihs

Madisch²,

Schlaud³

et al. 2003

Gesundheitswesen

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Whilst the prevalence of gastroesophageal reflux is increasing, most people are unaware of its possible consequences. Therefore, in Autumn 2000 a nationwide information campaign was launched on the symptoms of gastroesophageal reflux and its possible treatments. One part of the information campaign was a telephone hotline which was followed by an interview by phone or a mailed questionnaire. The objective of this was to find out more about the people concerned and their complaints. The subjects of both data sets were on average 53 respectively 57 years old, half of them were female and over 60 % had had heartburn for more than two years. The interview showed that 53 % took notice of the hotline by a press release. The interviewed persons gathered information in general about health-related issues primarily from newspapers and TV reports and from their physician. 81.7 % of the questionnaire sample had already at least one gastroscopy. Another 9.5 % made use of medical services because of their complaints in the last year. 8.8 % used exclusively over-the-counter medication for relief from their complaints. These three groups of different degrees of utilisation differed in respect of age, intensity and duration of the symptom heartburn and lifestyle-factors such as smoking. Those who had a gastroscopy were older, symptoms were more prolonged, more severe, more often and comprised a wider range of symptoms and less cigarette consumption. The analysis of both samples showed that the telephone hotline was used mainly by people who had had their symptoms for a long time and had already been in medical care. The chosen means of information stated by the sample indicate that media are prominently involved in disseminating information and educating the public.

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Reflux rising! A disease in evolution?

Cited by 15 publications

References 0 publications

Prevalence of Dysphagia in Patients with Gastroesophageal Reflux in Germany

Prevalence of Dysphagia in Patients with Gastroesophageal Reflux in Germany

The interplay between Helicobacter pylori, gastro-oesophageal reflux disease, and intestinal metaplasia

Sozialepidemiologische Analyse von Informationsquellen und medizinischer Versorgung einer Subpopulation von Teilnehmerinnen und Teilnehmern einer bundesweiten Informationskampagne „Alarmzeichen Sodbrennen”

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