Treatment targets for glycated hemoglobin (HbA 1c ), blood pressure and low-density lipoprotein cholesterol (LDL-C), and prescription of statins and of angiotensin-converting-enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) for patients with diabetes mellitus are recommended to reduce the risks of cardiovascular and microvascular complications. [1][2][3][4][5] The achievement of targets in Canada in more than 1 province was last evalu ated in 2013. At the time, HbA 1c , LDL-C and blood pressure targets were met for 50%, 57% and 36% of adults, respectively, with only 13% of adults meeting all 3 targets. 6,7 Women with diabetes have a disproportionately high relative increase in cardiovascular risk, [8][9][10][11][12] which may be partially explained by lower use of medications that reduce the risk of cardio vascular disease. [13][14][15][16] Few studies have tracked sex-and age-related differences in the achievement of diabetes targets. Updated information about sex-and age-related trends in target achievement in Canada will inform efforts to reduce cardiovascular risk among all eligible patients with diabetes. We aimed to describe the prevalence of diabetes measurements, and the frequency of target achievement and use of statins and ACE inhibitors or ARBs among adults with type 2 diabetes seen in primary care across 5 Canadian provinces in 2015 and 2020, and to evaluate the effect of age and sex on target achievement, adjusting for cardiovascular comorbidities.