“…For molecular fluids not subjected to large shear rates or large thermal gradients, there is a plateau of scales between the mean free path of the molecules and the minimally characteristic scales of macroscopic properties, where scaleindependent mass, momentum and energy densities and fluxes can be defined (Goldhirsch, 1999). However, many recent studies have shown that such plateau is non-existent in gas-solid two-phase flow, and the lack of scale-separation in both space and time were found (Agrawal et al, 2001;Andrews IV et al, 2005;De Wilde, 2005;Sundaresan, 2000;van der Hoef et al, 2006). These studies have shown that the effective inter-phase drag coefficient (or effective inter-phase slip velocity) and other properties are significantly dependent on the size of the periodic domain used in computer simulations.…”