Refraction in diabetics during metabolic dysregulation, acute or chronic

Abstract

The influence of diabetic dysregulation on refraction was analysed by a short-term and a long-term approach. a) Out of 15 patients admitted due to high blood sugars and followed over weeks, 11 showed refractive fluctuation of 1-6.5 D, in either direction-often with excess hypermetropia, while 4 appeared refractively stable. In those with refractive change a transient increase of lens thickness was suggested from ultrasound measurements. b) Diabetes control was evaluated retrospectively in 74 adult diabetics, mainly based on repeated 24 h urine glucose determinations over a 6-year period. As a group, those with low myopia did not score worse than those who had stayed emmetropic. Among the myopes, diabetes duration was longer in the subgroup where diabetes preceded myopia onset. - All considered, we found no support for dysregulation per se as an underlying factor behind the 'diabetic myopia' previously reported from our clinic.

Refractive properties of the healthy human eye during acute hyperglycemia

“…However, previous research has shown that hyperglycemia has no influence on the shape of the anterior corneal surface [10, 24, 29, 32]. The results of our study also agree with these findings.…”

Changes in straylight and corneal light scattering in a newly diagnosed case of type 2 diabetes

“…It has been found previously that people with diabetes have greater corneal light scattering than people without diabetes . The decreases in anterior chamber depth and increase in lens thickness during hyperglycaemia are in agreement with other studies …”

Transient Hyperopia after Intensive Treatment of Hyperglycemia in Newly Diagnosed Diabetes

“…Several reports have described the refractive changes associated with elevated or depressed blood glucose levels [4,5,6,7,8,9]. The correlation between the maximum hyperopic change of an eye and sex, age, duration of disease and type of hypoglycemic therapy was proved to be nonsignificant in the study by Okamoto et al [10].…”

“…However, Fledelius [6],Fledelius et al [7 ]and Eva et al[ 8] observed different refraction changes in diabetic patients with short- and long-term dysregulation; the refraction would become less myopic or more hyperopic while the plasma glucose concentration decreased rapidly. After the hyperopic change had appeared, the refractive normalization happened weeks behind the regulation of blood sugar.…”