Refractive associations with corneal biomechanical properties among young adults: a population-based Corvis ST study

Characterization of Corneal Biomechanics Using CORVIS ST Device in Different Grades of Myopia in a Sample of Middle Eastern Ethnicity

“… 32 In our study, we found only a statistically significant difference between the mild and moderate myopia groups, and CBI was correlated with SE; however, there was no correlation with SE or myopia grade in multivariate analysis. These results are consistent with those of other studies, 17 , 20 , 27 21 which did not find a significant correlation between SE and CBI. Therefore, CBI is affected more in cases of ectasia, regardless of refractive status.…”

“…In the current study, we found that SE was independently correlated with SSI, and we found a statistically significant difference in SSI between the mild, moderate myopia, and extreme myopia groups, consistent with the findings of Han et al, 18 who found that SSI values were lower in patients with higher grades of myopia; however, in their study, they included only two groups: the low myopia group with SE ≥ 3.00D and the high myopia group with SE > −6.00D, which is also consistent with other studies that involved extreme myopia patients among the Chinese population. 23 , 27 ,…”

“…These results are consistent with those of other studies, 18 , 20 , 22 also Lu et al 21 found a statistically significant correlation between axial length and PD in children; however, other studies testing the correlation between SE and PD found no significant results. 27 , 28 …”

“…12 A better understanding of corneal biomechanical characteristics in different grades of myopia might help improve the selection of suitable candidates for refractive procedures and guide the understanding of the management of biomechanic-modulating treatments. 13,14 Many studies 15,[16][17][18][19][20][21][22][23][24][25][26][27] have been conducted to detect the associations between corneal biomechanics measurements using Corvis ST in China, India, and Iran with few studies incorporating extreme myopia cases and few have addressed the value of SSI. The current study is the first to describe corneal biomechanical properties in different grades of myopia in our country and found that SSI and Peak distance were independently correlated with refractive error spherical equivalent, and SP-A was independently correlated with the grade of myopia.…”

“…These results are consistent with those of other studies, 18,20,22 also Lu et al 21 found a statistically significant correlation between axial length and PD in children; however, other studies testing the correlation between SE and PD found no significant results. 27,28 The stiffness parameter at applanation 1 (SP-A1) represents corneal stiffness as derived from the resultant pressure divided by the deflection amplitude at applanation 1(A1). 17 The more stiff the cornea, the more the value of SP-A1, in our study, we found that myopia grade was independently correlated with SP-A1 (coefficient p=−0.271, p=0.034), which is consistent with the results of other studies that analyzed SP-A1, 27 while other studies did not show a significant difference between different myopic grades.…”