Refractive Index Sensor Based on a Gradient Grating Period Guided-Mode Resonance

Hsiung, Chan-Te; Huang, Cheng-Sheng

doi:10.1109/lpt.2019.2890873

Cited by 14 publications

(9 citation statements)

References 25 publications

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“…The comparison is shown in Table 1 . As shown in Table 1 , the sensitivity of our sensor with very simple normal incidence achieved comparable sensitivity of other sensor [ 30 ]. Our sensor also operates at blue–violet wavelength (405 nm).…”

Section: Resultsmentioning

confidence: 59%

“…The optical RI sensing is one of the most suitable techniques for the applications mentioned above because the sensors do not require the electrical wiring. Many kinds type of RI optical sensing devices have been developed so far using optical resonances in metal surfaces [ 1 , 8 , 9 , 10 , 11 ], nano particles [ 2 , 3 , 12 , 13 , 14 ], nanorings [ 15 , 16 , 17 ], waveguides [ 18 , 19 , 20 , 21 , 22 ], gratings [ 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ], photonic crystals [ 31 , 32 , 33 , 34 ], and microstructured optical fibers [ 35 , 36 , 37 ]. The systems of RI sensing based on surface plasmon resonance (SPR) have been widely used and been commercialized.…”

Section: Introductionmentioning

confidence: 99%

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GaN-Based High-Contrast Grating for Refractive Index Sensor Operating Blue–Violet Wavelength Region

Takashima

Haraguchi

Naoi

2020

Sensors

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Owing to its versatility, optical refractive index (RI) sensors with compact size and high chemical stability are very suitable for a wide range of the applications in the internet of things (IoT), such as immunosensor, disease detection, and blood mapping. In this study, a RI sensor with very simple system and high chemical stability was developed using GaN-based high-contrast grating (HCG). The designed HCG pattern was fabricated on GaN-film grown on c-plane sapphire substrate. The fabricated GaN-HCG sensor can detect minuscule RI change of 1.71 × 10–3 with extreme simple surface normal irradiation system. The light behavior inside the GaN-HCG was discussed using numerical electromagnetic field calculation, and the deep understand of the sensing mechanism was provided. The simple system and very high chemical stability of our sensor exploit RI sensing applications in IoT society.

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Section: Resultsmentioning

confidence: 59%

Section: Introductionmentioning

confidence: 99%

GaN-Based High-Contrast Grating for Refractive Index Sensor Operating Blue–Violet Wavelength Region

Takashima

Haraguchi

Naoi

2020

Sensors

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“…By varying the grating period along the device length, our group developed a GGP-GMR device that essentially functions as a linear variable bandstop filter; the resonant wavelength also varies along the device length [12]. This device has subsequently been employed in spectral, displacement, fluorescent, and RI measurement applications as well as in LF biosensing [13,14,[29][30][31].…”

Section: Design Of the Ggp-gmr Sensormentioning

confidence: 99%

“…In 2016, our group proposed a linear variable bandstop filter based on a gradient grating period guidedmode resonance (GGP-GMR) [12]. This GGP-GMR filter was subsequently validated as a refractive index (RI) sensor [13] and a potential biosensor [14]. The chirped GMR or GGP-GMR converts spectral information into spatial information such that the signal can be directly read out by a charge-coupled device or complementary metal oxide semiconductor (CMOS) without a bulky spectrometer.…”

Section: Introductionmentioning

confidence: 99%

Handheld Biosensor System Based on a Gradient Grating Period Guided-Mode Resonance Device

Chiang,

Tseng,

Tsai

et al. 2023

Biosensors

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Handheld biosensors have attracted substantial attention for numerous applications, including disease diagnosis, drug dosage monitoring, and environmental sensing. This study presents a novel handheld biosensor based on a gradient grating period guided-mode resonance (GGP-GMR) sensor. Unlike conventional GMR sensors, the proposed sensor’s grating period varies along the device length; hence, the resonant wavelength varies linearly along the device length. If a GGP-GMR sensor is illuminated with a narrow band of light at normal incidence, the light resonates and reflects at a specific period but transmits at other periods; this can be observed as a dark band by using a complementary metal oxide semiconductor (CMOS) underneath the sensor. The concentration of a target analyte can be determined by monitoring the shift of this dark band. We designed and fabricated a handheld device incorporating a light-emitting diode (LED) light source, the necessary optics, an optofluidic chip with an embedded GGP-GMR sensor, and a CMOS. LEDs with different beam angles and bandpass filters with different full width at half maximum values were investigated to optimize the dark band quality and improve the accuracy of the subsequent image analysis. Substrate materials with different refractive indices and waveguide thicknesses were also investigated to maximize the GGP-GMR sensor’s figure of merit. Experiments were performed to validate the proposed handheld biosensor, which achieved a limit of detection (LOD) of 1.09 × 10−3 RIU for bulk solution measurement. The sensor’s performance in the multiplexed detection of albumin and creatinine solutions at concentrations of 0–500 μg/mL and 0–10 mg/mL, respectively, was investigated; the corresponding LODs were 0.66 and 0.61 μg/mL.

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“…In this work, we demonstrate a new type of smartphone biosensor system based on a gradient grating period (GGP) guided-mode resonance (GMR) biosensor [30,31]. The system works as follows: (1) An external LED is used to excite the resonance of the GGP-GMR sensor at normal incidence, simplifying the overall optical path design and minimizing the attachment volume.…”

Section: Introductionmentioning

confidence: 99%

Gradient Guided-Mode Resonance Biosensor with Smartphone Readout

Lin,

Chen,

Lei

et al. 2023

Biosensors

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Integrating biosensors with smartphones is becoming an increasingly popular method for detecting various biomolecules and could replace expensive laboratory-based instruments. In this work, we demonstrate a novel smartphone-based biosensor system with a gradient grating period guided-mode resonance (GGP-GMR) sensor. The sensor comprises numerous gratings which each correspond to and block the light of a specific resonant wavelength. This results in a dark band, which is observed using a CCD underneath the GGP-GMR sensor. By monitoring the shift in the dark band, the concentration of a molecule in a sample can be determined. The sensor is illuminated by a light-emitting diode, and the light transmitted through the GGP-GMR sensor is directly captured by a smartphone, which then displays the results. Experiments were performed to validate the proposed smartphone biosensor and a limit of detection (LOD) of 1.50 × 10−3 RIU was achieved for sucrose solutions. Additionally, multiplexed detection was demonstrated for albumin and creatinine solutions at concentrations of 0–500 and 0–1 mg/mL, respectively; the corresponding LODs were 1.18 and 20.56 μg/mL.

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Refractive Index Sensor Based on a Gradient Grating Period Guided-Mode Resonance

Cited by 14 publications

References 25 publications

GaN-Based High-Contrast Grating for Refractive Index Sensor Operating Blue–Violet Wavelength Region

GaN-Based High-Contrast Grating for Refractive Index Sensor Operating Blue–Violet Wavelength Region

Handheld Biosensor System Based on a Gradient Grating Period Guided-Mode Resonance Device

Gradient Guided-Mode Resonance Biosensor with Smartphone Readout

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