“…In one study, 7-22 % of cancer patients were judged to be good candidates for chemotherapy, were actively counseled about their disease, and were recommended for chemotherapy, yet refused it [12]. Patients refuse their physician's recommendation much more rarely regarding surgical and radiotherapy treatments for cancer (0.4 and 0.9 %, respectively), although a positive correlation does exist with increasing age [13,14]. Clearly the morbidity associated with chemotherapy carries with it a special stigma.…”