Regarding diarrhea in liver transplant recipients: Etiology and management.

Stelzmueller, Ingrid; Biebl, Matthias; Graziadei, I.; Wiesmayr, Silke; Margreiter, R; Bonatti, Hugo

doi:10.1002/lt.20665

Cited by 8 publications

(8 citation statements)

References 4 publications

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“…Diarrhea can last for 3–8 days, followed by asymptomatic shedding for 1–3 weeks . Viral spread commonly occurs fecal‐orally via water, person‐to‐person contact, or contaminated environmental surfaces . However, non‐fecal routes also play a role in transmission such as via respiratory droplets.…”

Section: Rotavirusmentioning

confidence: 99%

Diarrhea caused by viruses in transplant recipients

Lee

Ison

2014

Transplant Infectious Dis

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Diarrhea is a common complication after solid organ transplantation, and viruses are emerging as important but underestimated causative agents. Viral infections in solid organ transplant (SOT) recipients can result in severe and prolonged diarrhea with significant patient morbidity and graft complications. Cytomegalovirus remains the most common of the viruses to cause diarrhea, but other viruses are being increasingly recognized, including norovirus, rotavirus, and adenovirus. This article reviews the epidemiology, clinical presentation, diagnosis, management, and outcomes of these viral causes of diarrhea in SOT patients.

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Section: Rotavirusmentioning

confidence: 99%

Diarrhea caused by viruses in transplant recipients

Lee

Ison

2014

Transplant Infectious Dis

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“…In SOT recipients and other adult and pediatric immunosuppressed patients, outbreaks of rotavirus (RV) induced severe diarrhea have occurred [73][74][75][76] , associated with chronic infection and prolonged viral shedding. Infection with the intestinal nematode Strongyloides stercoralis, has been documented in renal transplant recipients with the majority of cases occurring within 3 months of transplantation 77 .…”

Section: Other Infectious Causesmentioning

confidence: 99%

Diarrhea in solid-organ transplant recipients: a review of the evidence

Pant

Deshpande

Larson

et al. 2013

Current Medical Research and Opinion

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Physicians should be familiar with the common etiologies that result in post-transplant diarrhea. A directed approach to diagnosis and treatment will not only help to resolve the diarrhea but also prevent potentially life-threatening consequences including loss of the graft as well. Prospective studies are required to determine the etiology of post-transplant diarrhea in different clinical and geographic settings.

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“…Data were collected and extracted from published cohort and case studies dated back from 1982 until recently and originated from Australia , Austria , Canada , France , Germany , India , Iran , Italy , Japan , Netherlands , Turkey , UK and USA (Table ). These patients were ranged in different age categories from very young to very old.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, specific treatment is not necessary . Nevertheless, when confronted with rotavirus‐infected transplantation patients, treatment with intensive care, rehydration, and replacement of nutrition and electrolytes is indicated , precisely because of the absence of specific therapy . Loperamide (one to two tablets and another tablet after every bowel movement) has been suggested for diarrhea control in adult organ transplant patients .…”

Section: Introductionmentioning

confidence: 99%

Rotavirus in Organ Transplantation: Drug-Virus-Host Interactions

Yin

Metselaar

Sprengers

et al. 2015

American Journal of Transplantation

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Although rotavirus is usually recognized as the most common etiology of diarrhea in young children, it can in fact cause severe diseases in organ transplantation recipients irrespective of pediatric or adult patients. This comprehensive literature analysis revealed 200 cases of rotavirus infection with 8 related deaths in the setting of organ transplantation been recorded. Based on published cohort studies, an average incidence of 3% (187 infections out of 6176 organ recipients) was estimated. Rotavirus infection often causes severe gastroenteritis complications and occasionally contributes to acute cellular rejection in these patients. Immunosuppressive agents, universally used after organ transplantation to prevent organ rejection, conceivably play an important role in such a severe pathogenesis. Interestingly, rotavirus can in turn affect the absorption and metabolism of particular immunosuppressive medications via several distinct mechanisms. Even though rotaviral enteritis is self‐limiting in general, infected transplantation patients are usually treated with intensive care, rehydration and replacement of nutrition, as well as applying preventive strategies. This article aims to properly assess the clinical impact of rotavirus infection in the setting of organ transplantation and to disseminate the interactions among the virus, host and immunosuppressive medications.

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Regarding diarrhea in liver transplant recipients: Etiology and management.

Cited by 8 publications

References 4 publications

Diarrhea caused by viruses in transplant recipients

Diarrhea caused by viruses in transplant recipients

Diarrhea in solid-organ transplant recipients: a review of the evidence

Rotavirus in Organ Transplantation: Drug-Virus-Host Interactions

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