Regenerative Medicine Treatments for Androgenetic Alopecia

Abstract

Regenerative medicine and the role of stem cells are being studied for applications in nearly every field of medicine. The pluripotent nature of stem cells underlies their vast potential for treatment of androgenic alopecia. Several advances in recent years have heightened interest in this field, chief among them are the evolution of simpler techniques to isolate regenerative elements and stems cells. These techniques are easy, outpatient procedures with immediate injection, often single session with harvest, and minimal manipulation (usually physical). This paper seeks to critically review the existing data and determine the current evidence and their role in practice.

Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review

“…Indeed, a variety of regenerative products can be generated from adipose tissue, including nano fat, vascular stem cell fraction (SVF), MSCs, adipose-derived stem cell conditioning medium (ADSC-CM), and extracellular veins (EV) [ 10 ]. The stromal vascular fraction (SVF) refers to all the cellular elements of the adipose tissue and is formed from heterogeneous cell population components of this tissue: adipocytes, blood cells, endothelial cells, extracellular matrix, and the most essential elements which are adipose-derived stromal/stem cells (ASC) [ 17 , 18 ]. Multipotent stem cells derived from adipose tissues, stromal vascular cells derived from adipose (ADSVC), or regenerative cells derived from adipose (ADRC) refer to the newly used primary multipotent stem cells derived from the stromal vascular fraction.…”