Regenerative Surgery in Open Mesh Repair for Inguinal Hernia

Nicola, Valerio Di

doi:10.37532/jrgm.2020.9(1).157

Cited by 2 publications

(4 citation statements)

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“…These PRP biological properties are increasingly used for OA treatments, maxillofacial and dental procedures, plastic surgery and aesthetic treatments and their use has recently been expanding in general surgery [8,9]. The final goal is the stimulation of resident MSCs to promote a regenerative microenvironment.…”

Section: Materials Employedmentioning

confidence: 99%

“…Inguinal hernia repair is the most frequently performed operation in General Surgery. Over 20 million hernia repair procedures per year are performed worldwide [8].…”

Section: Who Are the Rsu Patients? A Focus On Oa And Hernia Repairmentioning

confidence: 99%

“…Complications including chronic inguinal pain (12%) and recurrence rate (11%) have significant negative impact on surgical results. The 4 main impacting factors affecting hernia repair results are: 1) mesh material and design; 2) mesh fixation; 3) tissue healing and regeneration and 4) the surgical technique [8].…”

Section: Who Are the Rsu Patients? A Focus On Oa And Hernia Repairmentioning

confidence: 99%

“…These result in postoperative advantages. The short-term benefits are less pain and shorter time of recovery [8,9]. The mid-long-term benefits are lower incidence of chronic pain due to a correct process of wound healing and minimizing the risk of nerve entrapment [8,9].…”

Section: Who Are the Rsu Patients? A Focus On Oa And Hernia Repairmentioning

confidence: 99%

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Regenerative Surgery Unit (RSU) a new model of care

Nicola¹

2020

Biomed Res Clin Prac

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Regenerative Surgery (RS) defines all the Regenerative Medicine (RM) treatments that can be applied through minimally invasive surgical procedures. This biomedical approach includes the use of stem cells, various local biochemical mediators, and tissue engineering.The Regenerative Surgery Unit (RSU) is a new model of health care governance integrating clinical, scientific and research activities.RSU works in a multidisciplinary setting involving surgeon, biologist, immunologist, laboratory technician, radiologist, and physiotherapist.RSU setting also aims to generate a special relation between doctor and patient. The aim of this relationship is to establish a solid and mutually beneficial alliance, founded on medical ethics, between doctor and patient.RSU organises clinical services through ambulatory care and day surgery settings. The scientific and research activities are integrated as components of daily medical practice.This article describes some established procedures in RS and some refinements that are more recently available as a result of our clinical and research experience in RM fields.Health Tourism is one element of the sustainable growth model we are developing in the RSU-Villa Aurora Hospital, Foligno (Italy).

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Section: Materials Employedmentioning

confidence: 99%

“…Inguinal hernia repair is the most frequently performed operation in General Surgery. Over 20 million hernia repair procedures per year are performed worldwide [8].…”

Section: Who Are the Rsu Patients? A Focus On Oa And Hernia Repairmentioning

confidence: 99%

Section: Who Are the Rsu Patients? A Focus On Oa And Hernia Repairmentioning

confidence: 99%

Section: Who Are the Rsu Patients? A Focus On Oa And Hernia Repairmentioning

confidence: 99%

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Regenerative Surgery Unit (RSU) a new model of care

Nicola¹

2020

Biomed Res Clin Prac

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Platelet-Rich Fibrin-Mesh Technique for Inguinal Hernia Repair: Results of a Feasibility Pilot Study

Nicola

Tebala

2021

Surg Technol Int.

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Background: Open mesh repair is one of the most frequently performed general surgery operations worldwide. Unfortunately, the classic technique using stitches to fix the mesh is still associated with a high risk of chronic pain. We propose a new technique that uses autologous Platelet-Rich Fibrin (PRF) to fix the mesh. Methods: PRF is prepared in theatre by centrifugation of the patient’s own blood and immediately applied to fix the mesh. In this feasibility pilot study, five patients were operated upon with the PRF-mesh repair technique. Postoperative pain was evaluated with a visual analogue scale (VAS) up to 6 months after surgery. Time to recovery was also recorded for all patients. VAS in this small group of patients was grossly compared with that in a historical cohort of patients who underwent Lichtenstein repair; due to the small sample size, no statistical comparison was performed. Results: Postoperative pain remained at low levels and no patient experienced chronic pain, recurrence or any other complication within 6 months. All patients returned to their usual activities within 3 days after surgery. The VAS scores confirmed that PRF-mesh repair may be associated with less pain than the Lichtenstein technique. Conclusions: PRF-mesh repair is a safe and effective option in the treatment of inguinal hernias as it couples the safety of physiologically enhanced healing with the efficacy of prompt fixation of the mesh.

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Regenerative Surgery in Open Mesh Repair for Inguinal Hernia

Cited by 2 publications

References 0 publications

Regenerative Surgery Unit (RSU) a new model of care

Regenerative Surgery Unit (RSU) a new model of care

Platelet-Rich Fibrin-Mesh Technique for Inguinal Hernia Repair: Results of a Feasibility Pilot Study

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