RegentK Improves the Gait Mechanics of Patients with Acute Anterior Cruciate Ligament Rupture Immediately after Application: Clinical Trial

Abstract

Background: The purpose of this study was to investigate the immediate response to RegentK (Regeneration-Therapy by Khalifa) of patients with an acute rupture of the anterior cruciate ligament (ACL), regarding the gait mechanics and functional tests, in comparison to norm data. Patients and Methods: 9 male patients with an acute unilateral ACL rupture underwent an orthopedic exam and gait analysis immediately before and after the 1-h RegentK treatment; the results were compared to norm data of 10 healthy participants matched with the RegentK group for age and body mass index. An infrared camera system collected kinematic gait data on the injured limb; the gait kinetics were recorded with 2 force plates. Results: Immediately after the treatment, significant improvements with regard to limping, the quadriceps knee force, and the passive knee range of motion (ROM) occurred. The gait characteristics showed a significantly increased gait velocity (+0.17 m/s), step frequency (+8 steps/min), and injured-limb step length (+5 cm). The faster gait velocity involved increased sagittal ankle and hip ROM, increased maximal vertical ground reaction forces, internal ankle plantar flexion and hip flexion moments. Conclusions: RegentK seems to immediately affect functional parameters such as passive knee joint motion and quadriceps strength and seems to enable patients to walk more dynamically, generally expressed through an increased walking speed.

What is known about the RegentK regenerative treatment for ruptured anterior cruciate ligament? A scoping review

“…Analyzed studies indicate that RegentK therapy improves functional parameters such as passive mobility of the knee joint and quadriceps strength. Ofner et al [15,19] show that all but 1 patient increased their walking speed in a range of 3 to 68% (mean 18%), also increasing their stride length (range 0-38 cm, mean 10 cm). This improvement is explained mechanistically due to the RegentK treatment improving activation of the gastrocnemius and, consequently, this general muscular strategy can stabilize the injured knee joint [20].…”

“…The sensors were applied anterolaterally and anteromedially, beside the patella, on both the injured and the healthy (control) knee --10 male patients (mean age ± standard deviation 35.9 ± 6.1 years) using a fourchannel oximeter 7 Michael Ofner [15] 2017 -An infrared camera system collected kinematic gait data on the injured limb; the gait kinetics were recorded with two force plates --9 male patients with an acute unilateral ACL rupture underwent an orthopedic exam and gait analysis immediately before and after the 1-h RegentK treatment; the results were compared to norm data of 10 healthy participants matched with the RegentK group for age and body mass index…”

RegentK regenerative treatment available for ruptured anterior cruciate ligament? A scoping review

“…Analysed studies indicate that Regentk therapy improves functional parameters such as passive mobility of the knee joint and quadriceps strength. Ofner et al (12,13) show that all but 1 patient increased their walking speed in a range of 3 to 68% (mean: 18%), increasing also increased their stride length (range: 0-38 cm, mean: 10 cm). This improvement is explained as a mechanism due to the RegentK treatment improving the activation of the gastrocnemius and consequently this general muscular strategy can stabilise the injured knee joint (14).…”