Regio- and diastereoselective transition metal-free hydroalkylation of N-allenyl sulfonamides by push–pull 2-alkynylquinolines

Abstract

We describe a novel and efficient synthetic strategy to construct the linear homoallylic quinolone structures through the intramolecular addition of enolized 2-alkynylquinoline to allenamide. We developed the regio- and diastereoselective...