Regio- and stereoselective synthesis of the major metabolite of quercetin, quercetin-3-O-β-d-glucuronide

Mutational Analysis of the Medicago Glycosyltransferase UGT71G1 Reveals Residues That Control Regioselectivity for (Iso)flavonoid Glycosylation

“…The nature of the position of glycosylation significantly affects its absorption and utilization in humans (32)(33)(34). The chemical synthesis of specific quercetin glucosides is both complex and costly (35,36). Recently, there has been increasing interest in biocatalytic synthesis of glucosides of quercetin (27,37) and other phenolic compounds (38) due to their potential therapeutic value in cardiovascular disease and cancer, and their antimicrobial properties.…”

Computational approaches to the in vitro antibacterial activity of Allium hirtifolium Boiss against gentamicin-resistant Escherichia coli: focus on ribosome recycling factor

“…In silico findings showed that among phytocompounds found in bulbs of AH, shallomin has been docked with lower binding affinity with RRF with respect to gentamicin. Shallomin is a flavonoid and would be a new lead molecule in AH and has a wide range of antibacterial properties (Bouktaib et al 2002). Shallomin showed the lowest negative binding affinity against RRF among phytocompounds of AH.…”

Chemical composition and antioxidant ability of the crude extract of Sedum praealtum flowers

“…People use quercetin as a medicine (UMMC, 2012). It could be key in fighting several chronic degenerative diseases, circulation problems and preventing cancer (Bouktaib et al, 2002;Janisch, 2004). The oxidation of LDL is believed to play an important role in the pathogenesis of atherosclerosis and hence the risk of cardiovascular disease.…”