Region-based analysis with functional annotation identifies genes associated with cognitive function in South Asians from India
Hasan Abu-Amara,
Wei Zhao,
Zheng Li
et al.
Abstract:The prevalence of dementia among South Asians across India is approximately 7.4% in those 60 years and older, yet little is known about genetic risk factors for dementia in this population. Most known risk loci for Alzheimer's disease (AD) have been identified from studies conducted in European Ancestry (EA) but are unknown in South Asians. Using whole-genome sequence data from 2680 participants from the Diagnostic Assessment of Dementia for the Longitudinal Aging Study of India (LASI-DAD), we performed a gene… Show more
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