Regional and temporal heterogeneity of postsystolic wall thickening is associated with left ventricular asynchrony in normal and experimental stunned myocardium

Lucats, Laurence; Monnet, Xavier; Bizé, Alain; Chetboul, Valérie; Pouchelon, Jean‐Louis; Hittinger, Luc; Berdeaux, Alain; Ghaleh, Bijan

doi:10.1007/s00395-008-0716-1

Cited by 9 publications

(6 citation statements)

References 36 publications

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“…In addition, our values showed the same trend as those described in the literature with the lowest mean radial velocity values in the anteroseptal wall (20,21) and a decrease from apex to base (5). Accordingly, the ability of our technique to detect small physiological delays encourages its application in the context of myocardial ischemia (22) to help in objective detection of LV dysfunction. In such applications, increased values for mean transition times and decreased velocities are expected, as previously shown on a small number of patients with myocardial infarct (8).…”

Section: Discussionsupporting

confidence: 85%

Automated estimation of regional mean transition times and radial velocities from cine magnetic resonance images: Evaluation in normal subjects

El-Berbari¹,

Kachenoura²,

Redheuil³

et al. 2009

Magnetic Resonance Imaging

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Purpose:To assess regional ventricular function via an accurate and automated definition of functional parameters. Materials and Methods:An automated method is proposed that estimates reliable regional normalized mean transition times (F mc ) and mean radial velocities (V m ) from cine images. This approach combines a quantitative parametric imaging method and an automated detection of the endocardial border, which is robust to the presence of papillary muscles and nonhomogeneities within the left ventricular cavity. Steadystate free-precession cine-magnetic resonance imaging (MRI) of 36 healthy subjects was analyzed.Results: The quality of the automated segmentation was assessed on a subgroup of 20 subjects by comparing the results with the manual contours traced by an expert. The comparison of functional parameters estimated consequently using the automated and the manual contours yielded (y ϭ 0.959x ϩ 0.016, R ϭ 0.964) for F mc and (y ϭ 0.883x ϩ 0.505, R ϭ 0.935) for V m . On the entire group, F mc was equal to 0.392 Ϯ 0.069 and V m to 5.4 Ϯ 2.3 cm/s. Increasing values of the temporal parameter from the apex to the base and larger values in the septal wall than in lateral wall were demonstrated and were in accordance with the physiology. Conclusion:The proposed method ensures an automated and robust assessment of regional wall motion parameters, which could be clinically useful.

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Section: Discussionsupporting

confidence: 85%

Automated estimation of regional mean transition times and radial velocities from cine magnetic resonance images: Evaluation in normal subjects

El-Berbari¹,

Kachenoura²,

Redheuil³

et al. 2009

Magnetic Resonance Imaging

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“…Differences between normal and infarcted segments that were proved in [12] and [4] are confirmed here where both increased values for the normalized mean contraction times and decreased velocities in segments after myocardial infarct were observed when they are compared to values obtained on normal segments. When classifying the segments according to the different classes given by the expert, we can observe a link between the parameter values on a segment and the class to which it belongs.…”

Section: Discussionsupporting

confidence: 69%

An automated evaluation of regional left ventricular function on cine magnetic resonance images

Berbari

Kachenoura

Redheuil

et al. 2008

2008 Computers in Cardiology

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Routine evaluation of the regional ventricular function in cardiac magnetic resonance (CMR) remains mostly based on visual analysis of cine loops and subsequent interobserver variability remains a potential drawback for diagnosis and follow-up of coronary artery disease (CAD). In this paper we propose a method that ensures automated assessment of normalized mean contraction times and radial endocardial velocities from MR cine images, by combining a parametric imaging analysis to an automatic segmentation method of the left ventricle. Short-axis cine loops were obtained in 20 subjects (10 myocardial infarction (MI) and 10 control). Reference segmental wall motion was scored by an expert according to 4 classes (normokinesia, hypokinesia, akinesia and dyskinesia). Results showed increased values for normalized mean contraction times and decreased values for the radial velocity in segments with wall motion abnormalities (WMA) compared to segments with normal function. These functional parameters could help to detect regional WMA.

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“…Abbreviation as in Figure 4. Lucats et al (14) have demonstrated that PST derived from sonomicrometry in a dog model is observed in the posterior wall even at baseline. In our results, however, PST was hardly detected in the LCX regions at baseline.…”

Section: Recovery Of Pst After Relief From Myocardial Ischemiamentioning

confidence: 98%

Assessment of Myocardial Ischemic Memory Using Persistence of Post-Systolic Thickening After Recovery From Ischemia

Asanuma

Uranishi

Masuda

et al. 2009

JACC: Cardiovascular Imaging

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Regional and temporal heterogeneity of postsystolic wall thickening is associated with left ventricular asynchrony in normal and experimental stunned myocardium

Cited by 9 publications

References 36 publications

Automated estimation of regional mean transition times and radial velocities from cine magnetic resonance images: Evaluation in normal subjects

Automated estimation of regional mean transition times and radial velocities from cine magnetic resonance images: Evaluation in normal subjects

An automated evaluation of regional left ventricular function on cine magnetic resonance images

Assessment of Myocardial Ischemic Memory Using Persistence of Post-Systolic Thickening After Recovery From Ischemia

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