Regional anesthesia as part of enhanced recovery strategies in pediatric cardiac surgery

Yamamoto, Tohei; Schindler, Ehrenfried

doi:10.1097/aco.0000000000001262

Cited by 5 publications

(3 citation statements)

References 66 publications

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“…Efficient perioperative pain relief is essential for realising enhanced recovery strategies. Perioperative pain management using additional peripheral nerve blocks has been reported to ensure early extubation and a shorter intensive care and hospitalization times [11].…”

Section: Introductionmentioning

confidence: 99%

Comparison between Ultrasonographic-Guided Temporal and Coronoid Approaches for Trigeminal Nerve Block in Dogs: A Cadaveric Study

Gutiérrez Bautista,

Mikic,

Otero

et al. 2024

Preprint

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The trigeminal nerve is responsible for innervating the periorbita. Ultrasound-guided trigeminal block is employed in humans for trigeminal neuralgia or periorbital surgery. There are no studies evaluating this block in dogs. This study aims to evaluate and compare two approaches (coronoid and temporal) of the trigeminal nerve block. We hypothesized superior staining with the coronoid approach. Thirteen dog heads were used. After a preliminary anatomical study, two ultrasound-guided injections per head (right and left, coronoid and temporal approach, randomly assigned), with an injectate volume of 0.15 mL cm-1 of cranial length were performed (iodate contrast and tissue dye mixture). The ultrasound probe was placed over the temporal region, visualizing the pterygopalatine fossa. For the temporal approach, the needle was advanced from the medial aspect of the temporal region in a dorsoventral direction. For the coronoid approach, it was advanced ventral to the zygomatic arch in a lateromedial direction. CT scans and dissections were conducted to assess and compare the position of the needle, spread of injectate, and nerve staining. No significant differences were found. Both approaches demonstrated effective interfascial distribution of injectate, with some minimal intracranial spread. Although the coronoid approach did not yield superior staining as hypothesized, it presents a viable alternative to the temporal approach. Studies in live animals are warranted to evaluate clinical efficacy and safety.

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Section: Introductionmentioning

confidence: 99%

Comparison between Ultrasonographic-Guided Temporal and Coronoid Approaches for Trigeminal Nerve Block in Dogs: A Cadaveric Study

Gutiérrez Bautista,

Mikic,

Otero

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Efficient perioperative pain relief is essential for realising enhanced recovery strategies. Perioperative pain management using additional peripheral nerve blocks has been reported to ensure early extubation and shorter intensive care and hospitalisation times [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison between Ultrasonographic-Guided Temporal and Coronoid Approaches for Trigeminal Nerve Block in Dogs: A Cadaveric Study

Gutiérrez Bautista,

Mikic,

Otero

et al. 2024

Animals

View full text Add to dashboard Cite

The trigeminal nerve is responsible for innervating the periorbita. Ultrasound-guided trigeminal block is employed in humans for trigeminal neuralgia or periorbital surgery. There are no studies evaluating this block in dogs. This study aims to evaluate and compare two approaches (coronoid and temporal) of the trigeminal nerve block. We hypothesised superior staining with the coronoid approach. Thirteen dog heads were used. After a preliminary anatomical study, two ultrasound-guided injections per head (right and left, coronoid and temporal approach, randomly assigned), with an injectate volume of 0.15 mL cm−1 of cranial length, were performed (iodinated contrast and tissue dye mixture). The ultrasound probe was placed over the temporal region, visualising the pterygopalatine fossa. For the temporal approach, the needle was advanced from the medial aspect of the temporal region in a dorsoventral direction. For the coronoid approach, it was advanced ventral to the zygomatic arch in a lateromedial direction. CT scans and dissections were conducted to assess and compare the position of the needle, the spread of the injectate, and nerve staining. No significant differences were found. Both approaches demonstrated the effective interfascial distribution of the injectate, with some minimal intracranial spread. Although the coronoid approach did not yield superior staining as hypothesised, it presents a viable alternative to the temporal approach. Studies in live animals are warranted to evaluate clinical efficacy and safety.

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“…Currently, local anesthesia is an effective strategy for perioperative pain management. [ 3 , 4 ] However, due to the high effective drug concentration required for anesthetic drugs, using traditional single‐injection anesthetic drugs exhibits significant limitations, including short effective analgesia and systemic toxicity. [ 5 , 6 ] To address these issues, clinical attempts have been made, such as by implanting catheters for continuous administration, which might inconvenient, expensive, technically demanding, and might increase the risks of infections and nerve injury.…”

Section: Introductionmentioning

confidence: 99%

Injectable Hydrogel Delivery System with High Drug Loading for Prolonging Local Anesthesia

Li,

Chen,

Xue

et al. 2024

Advanced Science

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Peripheral nerve block is performed for precise pain control and lesser side effects after surgery by reducing opioid consumption. Injectable hydrogel delivery systems with high biosafety and moisture content have good clinical application prospects for local anesthetic delivery. However, how to achieve high drug loading and long‐term controlled release of water‐soluble narcotic drugs remains a big challenge. In this study, heterogeneous microspheres and an injectable gel‐matrix composite drug delivery system are designed in two steps. First, heterogeneous hydrogel microspheres loaded with ropivacaine (HMS‐ROP) are prepared using a microfluidic chip and in situ alkalization. An injectable self‐healing hydrogel matrix (Gel) is then prepared from modified carboxymethylcellulose (CMC‐ADH) and oxidized hyaluronic acid (OHA). A local anesthetic delivery system, Gel/HMS‐ROP/dexmedetomidine (DEX), with long‐term retention and drug release in vivo is prepared by combining HMS‐ROP and Gel/DEX. The drug loading of HMS‐ROP reached 41.1%, with a drug release time of over 160 h in vitro, and sensory and motor blockade times in vivo of 48 and 36 h, respectively. In summary, the sequential release and synergistic analgesic effects of the two anesthetics are realized using core‐shell microspheres, DEX, and an injectable gel, providing a promising strategy for long‐acting postoperative pain management.

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Regional anesthesia as part of enhanced recovery strategies in pediatric cardiac surgery

Cited by 5 publications

References 66 publications

Comparison between Ultrasonographic-Guided Temporal and Coronoid Approaches for Trigeminal Nerve Block in Dogs: A Cadaveric Study

Comparison between Ultrasonographic-Guided Temporal and Coronoid Approaches for Trigeminal Nerve Block in Dogs: A Cadaveric Study

Comparison between Ultrasonographic-Guided Temporal and Coronoid Approaches for Trigeminal Nerve Block in Dogs: A Cadaveric Study

Injectable Hydrogel Delivery System with High Drug Loading for Prolonging Local Anesthesia

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