Regional Anesthetic Techniques for Postoperative Analgesia

Dean, Robert

doi:10.1016/s0899-5885(18)30755-x

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Utilization Of Co-axial Narcotics1

Introduction1

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1999

2001

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Cited by 2 publications

(2 citation statements)

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“…Epidural narcotics are administered intermittently or continuously into the epidural space. If proper sterile technique is maintained, an epidural catheter can be utilized to administer narcotics up to seven days (Dean, 1991).…”

Section: Utilization Of Co-axial Narcoticsmentioning

confidence: 99%

A Descriptive Study of a Perioperative Pain Service Program

Bell¹

1999

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Section: Utilization Of Co-axial Narcoticsmentioning

confidence: 99%

A Descriptive Study of a Perioperative Pain Service Program

Bell¹

1999

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“…cardiopulmonary and metabolic processes) and endocrine functions (Murakami et al., 1984; Murakawa et al., 1989; Tsui et al., 1997; Barratt et al., 1999). Adequate post‐operative pain control would provide earlier recovery from surgery and improve patient outcome (Dean, 1991; Hendrix et al., 1996).…”

Section: Introductionmentioning

confidence: 99%

Epidural Analgesia with a Combination of Bupivacaine and Buprenorphine in Rats

Morimoto¹,

Nishimura

Matsunaga

et al. 2001

Journal of Veterinary Medicine Series A

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We determined the analgesic effects of epidural administration of either bupivacaine at 62.5, 125, 250, and 500 micrograms/kg; buprenorphine at 5 and 10 micrograms/kg; and the combination of bupivacaine at 125 micrograms/kg and buprenorphine at 5 or 10 micrograms/kg, using the tail flick (TF) and colorectal distension (CD) tests in rats and compared the results with those obtained using morphine at 100 micrograms/kg. In both the TF and CD tests, all doses of bupivacaine alone produced potent anti-nociceptive effects, although the effect rapidly diminished after 20-30 min of administration. The administration of buprenorphine at 10 and 5 micrograms/kg produced mild to moderate anti-nociceptive effects in both the TF and CD tests, and the effects were relatively constant throughout the 2-h experimental period. Combinations of 5 or 10 micrograms/kg of buprenorphine with 125 mg/kg of bupivacaine produced a significantly higher percentage of maximum possible analgesic effect (%MPE) than that of the calculated additive effect of each drug alone in the TF and CD tests. The analgesic effect of this combination was similar to that of morphine. Minimal ataxia was observed in rats administered this combination.

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Regional Anesthetic Techniques for Postoperative Analgesia

Cited by 2 publications

References 20 publications

A Descriptive Study of a Perioperative Pain Service Program

A Descriptive Study of a Perioperative Pain Service Program

Epidural Analgesia with a Combination of Bupivacaine and Buprenorphine in Rats

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