Regional Cerebral Blood Flow After Human Cardiac Arrest

Roine, Risto O.; Launes, Jyrki; Nikkinen, Päivi; Lindroth, L.; Kaste, Markku

doi:10.1001/archneur.1991.00530180081021

Cited by 50 publications

(6 citation statements)

References 24 publications

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“…Despite its cause, the hypofrontal pattern observed in our comatose patients was common to both in diffuse and in focal lesions, and thus it seems lacking of any prognostic significance. Similar data have been recently reported by Roine et al [33] in comatose patients after cardiac arrest.…”

Section: Discussionsupporting

confidence: 91%

Quantitative cerebral blood flow and metabolism determination in the first 48 hours after severe head injury with a new dynamic spect device

et al. 1997

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CBF in the first 48 hours after trauma varies within a large range of values and is not correlated with severity and prognosis. Clinical evaluation with GCS and CMRO2 are much more reliable indicators of severity of head trauma and have a significant role in the determination of prognosis. F/O ration is significantly altered from normal values confirming "post-traumatic hypofrontalism" but does not correlate with severity and prognosis.

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Section: Discussionsupporting

confidence: 91%

Quantitative cerebral blood flow and metabolism determination in the first 48 hours after severe head injury with a new dynamic spect device

et al. 1997

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“…Patients with a total perfusion deficit size of more than 50% of the supratentorial brain remained comatose and died, but even large perfusion deficits up to 40% did not exclude the possibility of good recovery. The occur rence or severity of frontal hypoperfusion did not predict either the recovery of consciousness or the outcome [85].…”

Section: P Rognostic Impact Of Imeuroimaging Testsmentioning

confidence: 79%

The Prognostication of Cerebral Hypoxia after Out-of-Hospital Cardiac Arrest in Adults

1997

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Early determination of outcome after out-of-hospital cardiopulmonary resuscitation is a common problem with great ethical, economic, social and legal consequences. Although there has been a fulminant development of emergency medicine during the last three decades, severe cerebral damage sometimes cannot be avoided. For neurological outcome prediction after cardiac arrest clinical neurological signs, electrophysiological examinations, neuroimaging tests, and laboratory parameters in serum and cerebrospinal fluid are used today, nevertheless, there still remains a considerable degree of uncertainty. However, although prognostic criteria which enable the clinician to stop treatment cannot be given at the present time, useful applications of early prognostication after cardiac arrest range from counseling of families, triage decisions, and do-not-resuscitate decisions to future clinical investigations of brain resuscitative measures.

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“…SPET using 99mTc-HMPAO, which provides a means of imaging regional cerebral blood flow (rCBF) and metabolism, has been used to evaluate patients who have suffered cardiac arrest [2], cerebral vascular accident [3,4], traumatic brain injury [5][6][7], and Alzheimer's disease and other diseases that cause memory problems [8][9][10]. Many of these patients, mainly of the older age group, may have associated brain atrophy and atrophy per se can produce alterations 447 in the perfusion pattern of the brain.…”

Section: Discussionmentioning

confidence: 99%

Signs of cerebral atrophy on single-photon emission tomography

1994

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Cerebral atrophy often coexists with other brain disorders and by itself may alter the pattern of cerebral perfusion. If unrecognized, it may confound diagnoses based on brain single-photon emission tomography (SPET). In this retrospective study, we describe and evaluate criteria for the diagnosis of cerebral atrophy on technetium-99m hexamethylpropylene amine oxime brain SPET studies. The SPET scans of 11 patients with cerebral atrophy and ten controls were evaluated for the presence of a prominent interhemispheric fissure, presence of prominent cerebral sulci, separation of thalamic nuclei, and pronounced separation of caudate nuclei. The SPET studies were interpreted by two independent observers blind to the findings of magnetic resonance imaging, which provided the final diagnosis of cerebral atrophy. The combination of the four scintigraphic signs was accurate in the diagnosis of cerebral atrophy in 95% of the cases and had a sensitivity of 91% and a specificity of 100%.

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Regional Cerebral Blood Flow After Human Cardiac Arrest

Cited by 50 publications

References 24 publications

Quantitative cerebral blood flow and metabolism determination in the first 48 hours after severe head injury with a new dynamic spect device

Quantitative cerebral blood flow and metabolism determination in the first 48 hours after severe head injury with a new dynamic spect device

The Prognostication of Cerebral Hypoxia after Out-of-Hospital Cardiac Arrest in Adults

Signs of cerebral atrophy on single-photon emission tomography

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