Regional Curvature Analysis in the Left Ventricle of the Heart using Hotelling T2 Metric

Abstract

This paper proposes a method for local deformation analysis of the heart's left ventricle (LV) which is of an utmost interest in characterizing the myocardium disease extent and severity. Our method is based on regional curvature variation calculation using the Hotelling T2 two samples difference metric. Our approach is validated on real data obtained from myocardial scintigraphy imaging technique. The curvature variation is calculated at stress and rest. Experimental results demonstrate the effectiveness and the validity of our approach.